Mouse CX3CR1 Allophycocyanin Affinity Purified PAb (100 TESTS)【科瑞奥博】

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Mouse CX3CR1 Allophycocyanin Affinity Purified PAb (100 TESTS)

货号： FAB5825A-100 基本售价： 4947.3 元规格： 100 Tests

产品信息

概述
货号	FAB5825A-100
别名	Beta chemokine receptor-like 1; CCRL1; chemokine (C-C) receptor-like 1; chemokine (C-X3-C motif) receptor 1; chemokine (C-X3-C) receptor 1; CMKbRL1; CMK-BRL1; CMK-BRL-1; CMKDR1; CX3C chemokine receptor 1; Fractalkine receptor; G protein-coupled receptor 13; GPR13G-protein coupled receptor 13; GPRV28; V28; V28C-X3-C CKR-1
全称	CX3C Chemokine Receptor 1
反应种属	Mouse
应用	Flow Cytometry(10 µL/10⁶cells)
目标/特异性	Detects mouse CX3CR1 in direct ELISAs. Stains mouse CX3CR1 transfectants but not irrelevant transfectants in flow cytometry.
使用方法	Flow Cytometry: 10 µL/10⁶cells
来源	The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
产品组分

性能
供应商	R&D Systems
Entrez Gene IDs	1524 (Human); 13051 (Mouse); 171056 (Rat)
应用文献
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions. CXCR4 expression on pathogenic T cells facilitates their bone marrow infiltration in a mouse model of aplastic anemia. Authors: Arieta Kuksin C, Gonzalez-Perez G, Minter L Blood, 2015;125(13):2087-94. Species: Mouse Sample Type: Whole Cells Application: Flow
纯化方式	Antigen Affinity-purified
免疫原	E. coli-derived recombinant mouse CX3CR1 Met1-Thr32, Leu92-Lys104, Thr169-Val196, Lys258-Leu274 Accession # Q9Z0D9
生物活性	Mouse
标记	APC
背景	CX3CR1 (CX₃C chemokine receptor 1; also fractalkine receptor, GPCR13 and V28) is a 40 kDa member of the δ-group of rhodopsin GPCRs. It is expressed on astrocytes, microglia, macrophages, Th1 and Tc1 T cells, NK cells, mouse Gr1^lo monocytes plus smooth muscle and mast cells. CX₃CR1 mediates adhesion to fractalkine, promotes avid binding of integrins to their ligands, and extends the life of monocytes. Mouse CX3CR1 is a 7-transmembrane protein that is 354 amino acids (aa) in length. It contains a 32 aa N-terminal extracellular region that shows no glycosylation, and a 56 aa C-terminal cytoplasmic domain. Over aa 1‑32, 91‑104, 169‑196 and 258‑274 collectively, mouse CX₃CR1 shares 96% and 77% aa identity with rat and human CX₃CR1, respectively.
运输条件	Blue Ice
存放说明	4℃
参考文献	Cancer Stem Cell Markers Chemokine Nomenclature Chemokine Receptors Chemokines and Receptors Chemokines and Receptors in Allergy and Asthma Chemokines and Receptors in Angiogenesis Conventional/Classical Dendritic Cells Glomerulonephritis: Beyond Inflammation Mini-review: Chemokines III Monocyte Markers Mouse Tissue-Resident Macrophage Markers Neutrophils Renal Markers T Cell Migration/Adhesion

参考图片

Detection of CX3CR1 in Mouse Splenocytes by Flow Cytometry. Mouse splenocytes were stained with Goat Anti-Mouse CX3CR1 APC‑conjugated Antigen Affinity-purified Polyclonal Antibody (Catalog # FAB5825A) and Anti-Mouse Integrin alpha X/CD11c PE-conjugated Monoclonal Antibody. Quadrant markers were set based on control antibody staining (Catalog # IC108A). View our protocol for Staining Membrane-associated Proteins.

Detection of CX3CR1 in CHO Chinese Hamster Cell Line Transfected with Mouse CX3CR1 and eGFP by Flow Cytometry. CHO Chinese hamster ovary cell line transfected with either
(A) mouse CX3CR1 or (B) irrelevant transfectants and eGFP was stained with Goat Anti-Mouse CX3CR1 APC‑conjugated Antigen Affinity-purified Polyclonal Antibody (Catalog # FAB5825A). Quadrant markers were set based on control antibody staining (Catalog # IC108P). View our protocol for Staining Membrane-associated Proteins.