Mouse S1P1/EDG-1 Allophycocyanin MAb (Clone 713412) (100 TESTS)【科瑞奥博】

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Mouse S1P1/EDG-1 Allophycocyanin MAb (Clone 713412) (100 TESTS)

货号： FAB7089A 基本售价： 4808.5 元规格： 100 Tests

产品信息

概述
货号	FAB7089A
别名	CD363 antigen; CD363; CHEDG1; D1S3362; EDG1; EDG-1; EDG1edg-1; Endothelial differentiation G-protein coupled receptor 1; endothelial differentiation, sphingolipid G-protein-coupled receptor, 1; FLJ58121; S1P receptor 1; S1P receptor Edg-1; s1p1; S1P1ECGF1; S1PR1; sphingosine 1-phosphate receptor 1; sphingosine 1-phosphate receptor EDG1; Sphingosine 1-phosphate receptor Edg-1; sphingosine-1-phosphate receptor 1
全称	Endothelial Differentiation Gene 1
反应种属	Mouse
应用	Flow Cytometry(10 µL/10⁶cells)
目标/特异性	Detects mouse S1P₁/EDG‑1 peptide in direct ELISAs.
使用方法	Flow Cytometry: 10 µL/10⁶cells
来源	The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
产品组分

性能
供应商	R&D Systems
Entrez Gene IDs	1901 (Human); 13609 (Mouse)
应用文献
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions. IL4RA on lymphatic endothelial cells promotes T cell egress during sclerodermatous graft versus host disease JCI Insight, 2016;1(12):. Species: Mouse Sample Type: Whole Cells Application: Flow Targeting of Ly9 (CD229) Disrupts Marginal Zone and B1 B Cell Homeostasis and Antibody Responses. Authors: Cuenca M, Romero X, Sintes J, Terhorst C, Engel P J Immunol, 2016;196(2):726-37. Species: Mouse Sample Type: Whole Cells Application: Flow Intravenous gammaglobulin inhibits encephalitogenic potential of pathogenic T cells and interferes with their trafficking to the central nervous system, implicating sphingosine-1 phosphate receptor 1-mammalian target of rapamycin axis. Authors: Othy S, Hegde P, Topcu S, Sharma M, Maddur M, Lacroix-Desmazes S, Bayry J, Kaveri S J Immunol, 2013;190(9):4535-41. Species: Mouse Sample Type: Whole Cells Application: Flow
纯化方式	Protein A or G purified from hybridoma culture supernatant
免疫原	Mouse S1P₁/EDG‑1 synthetic peptide (T4-H28) Accession # O08530
生物活性	Mouse
标记	Allophycocyanin
背景	S1P₁ (sphingosine 1-phosphate receptor-1), also known as EDG-1 (endothelial differentiation, G-protein coupled receptor-1) or S1PR1 (sphingosine-1-phosphate receptor 1) is a widely expressed, 37-40kDa, G protein coupled receptor within the S1P subfamily of the EDG family. S1P₁is one of five receptors for the bioactive lipid S1P and mediates most of S1Peffects on angiogenesis, vascular maturation, and cell migration, especially Tcell egress from lymphoid organs. Human and mouse S1P₁ share 84% amino acididentity within the N-terminal extracellular portion used as an immunogen.
运输条件	Blue Ice
存放说明	4℃
参考文献	B Cell Chemotaxis, Migration, and Adhesion Bioactive Lipid G Protein-Coupled Receptors Endothelial Cell Differentiation Markers Endothelial Cell Markers Endothelial Cell Markers and Adhesion Molecules in Angiogenesis Endothelial Progenitor and Endothelial Cell Markers ICC / IHC Images: S1P1/EDG-1 Natural Killer T (NKT) Cells Steroid Hormones and Bioactive Lipids T Cell Migration/Adhesion

参考图片

Detection of S1P₁/EDG‑1 in HEK293 Human Cell Line Transfected with S1P₁/EDG-1 and eGFP by Flow Cytometry. HEK293 human embryonic kidney cell line transfected with S1P₁/EDG-1 and eGFP was stained with either (A) Rat Anti-Mouse S1P₁/EDG‑1 APC‑conjugated Monoclonal Antibody (Catalog # FAB7089A) or (B) Rat IgG_2A Allophycocyanin Isotype Control (Catalog # IC006A). View our protocol for Staining Membrane-associated Proteins.

Detection of S1P₁/EDG‑1 in Mouse Thymocytes by Flow Cytometry. Mouse thymocytes were stained with Rat Anti-Mouse CD4 PE‑conjugated Monoclonal Antibody (Catalog # FAB554P) and either (A) Rat Anti-Mouse S1P₁/EDG‑1 APC‑conjugated Monoclonal Antibody (Catalog # FAB7089A) or (B) Rat IgG_2A Allophycocyanin Isotype Control (Catalog # IC006A). View our protocol for Staining Membrane-associated Proteins.