货号 | FAB53681C |
别名 | CDw210b antigen; CDw210b; CRF2-4IL-10R subunit 2; CRFB4; CRFB4human transmembrane receptor protein; cytokine receptor10CDW210B; D21S58; D21S66; IBD25; IL-10 receptor subunit beta; IL-10R2; IL-10R2IL-10R subunit beta; IL10RB; IL-10RB; interleukin 10 receptor, beta; Interleukin-10 receptor subunit 2; interleukin-10 receptor subunit beta; member 4 | 全称 | Interleukin 10 Receptor beta |
反应种属 | Mouse |
应用 | Flow Cytometry(10 µL/106cells) |
目标/特异性 | Detects mouse IL-10 R beta in direct ELISAs. |
使用方法 | Flow Cytometry: 10 µL/106cells |
来源 | The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below. |
产品组分 |
供应商 | R&D Systems |
Entrez Gene IDs | 3588 (Human); 16155 (Mouse) |
纯化方式 | Protein A or G purified from hybridoma culture supernatant |
免疫原 | Mouse myeloma cell line NS0-derived recombinant mouse IL-10 R beta Ile21-Ser220 Accession # Q61190 |
生物活性 | Mouse |
标记 | PerCP |
背景 | IL-10 R beta (Interleukin 10 receptor beta; also IL-10R2, CD210b and CRF2-4) is an 80-85 kDa member of the type II cytokine receptor family of proteins. It is very widely expressed and serves as a signal transducing accessory chain when complexed to the ligand-binding chains for IL-10, -22, -28A, -28B, and -29 (plus IL-26 in human). Mature mouse IL-10 R beta is a type I transmembrane protein with an extracellular domain that possesses two fibronectin type III domains (aa 22-107 and 111‑208). There is one alternate start site at Met20. Over aa 21- 220, mouse IL-10 R beta shares 87% and 74% aa identity with rat and human IL-10 R beta, respectively. |
运输条件 | Blue Ice |
存放说明 | 4℃ |
参考文献 |
|
Detection of IL‑10 R beta in EL4.IL-2 Mouse Cell Line by Flow Cytometry. EL4.IL-2 mouse lymphoblast cell line was stained with Rat Anti-Mouse IL‑10 R beta PerCP‑conjugated Monoclonal Antibody (Catalog # FAB53681C, filled histogram) or isotype control antibody (Catalog # IC006C, open histogram). View our protocol for Staining Membrane-associated Proteins. |