货号 | FAB4499G |
别名 | CCK4; CCK-4; CCK4Colon carcinoma kinase 4; colon carcinoma kinase-4; Protein-tyrosine kinase 7; Pseudo tyrosine kinase receptor 7; PTK7 protein tyrosine kinase 7; Tyrosine-protein kinase-like 7 | 全称 | Protein Tyrosine Kinase 7 |
反应种属 | Human/Rat |
应用 | Flow Cytometry(5 µL/106cells) |
目标/特异性 | Detects human and rat PTK7/CCK4 in Western blots. |
使用方法 | Flow Cytometry: 5 µL/106cells |
来源 | The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below. |
产品组分 |
供应商 | R&D Systems |
Entrez Gene IDs | 5754 (Human); 71461 (Mouse); 301242 (Rat) |
纯化方式 | Protein A or G purified from hybridoma culture supernatant |
免疫原 | E. coli-derived recombinant human PTK7/CCK4 Ala31-Ser199 Accession # Q13308 |
生物活性 | Human, Rat |
标记 | Alexa Fluor 488 |
背景 | Protein tyrosine kinase 7 (PTK7), also known as colon carcinoma kinase 4 (CCK4), is a receptor tyrosine kinase (RTK) involved in colon carcinoma development and/or proliferation. Similar to the RTK HER3, PTK7 contains a catalytically inactive tyrosine kinase domain, suggesting a potential tumor-characteristic role as a signal amplifier or modulator for an as yet unidentified kinase-competent partner. PTK7 may also play a role during gastrulation in the rodent embryo. |
运输条件 | Blue Ice |
存放说明 | 4℃ |
参考文献 |
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Detection of PTK7/CCK4 in HepG2 Human Cell Line by Flow Cytometry. HepG2 human hepatocellular carcinoma cell line was stained with Mouse Anti-Human/Rat PTK7/CCK4 Alexa Fluor® 488‑conjugated Monoclonal Antibody (Catalog # FAB4499G, filled histogram) or isotype control antibody (Catalog # IC002G, open histogram). View our protocol for Staining Membrane-associated Proteins. |