Mouse Complement C5a R1 Allophycocyanin MAb (Cl 583837) (100 TESTS)
货号：
FAB6467A 基本售价：
4808.5 元 规格：
100 Tests
产品信息
概述| 货号 | FAB6467A |
| 别名 | C5a anaphylatoxin chemotactic receptor; C5A; C5aR; C5a-R; C5AR1; C5ARC5a anaphylatoxin receptor; C5R1C5a ligand; CD88 antigen; CD88; complement component 5 receptor 1 (C5a ligand); complement component 5 receptor 1; complement component 5a receptor 1 |
全称 | Complement Component C5a Receptor 1 | | 反应种属 | Mouse |
| 应用 | Flow Cytometry |
| 目标/特异性 | This antibody detects mouse Complement Component C5a R1 in direct ELISAs.
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| 使用方法 | Flow Cytometry: 10 µL/106cells
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| 来源 | The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below. |
| 产品组分 | |
性能| 供应商 | R&D Systems |
| Entrez Gene IDs | 728 (Human); 12273 (Mouse) |
| 纯化方式 | Protein A or G purified from hybridoma culture supernatant |
| 免疫原 | NS0 mouse myeloma cell line transfected with mouse Complement Component C5a R1
Accession # P30993 |
| 生物活性 | Mouse |
| 标记 | Allophycocyanin |
| 背景 | Complement Component C5a R1, also known as C5a ligand and CD88, is a 7TM protein expressed on myeloid, endothelial, epithelial, and smooth muscle cells. C5a R1 binds the activated complement anaphylatoxin C5a. In established allergic environments, this triggers neutrophil and eosinophil chemotaxis and the release of proinflammatory mediators. In contrast, C5a R1/C5a interactions are protective during allergen sensitization. Mouse C5a R1 shares 66% and 77% amino acid sequence identity with human and rat C5a R, respectively. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 参考文献 | - Complement Pathway
- Human CD Marker Products
- Myeloid-derived Suppressor Cells (MDSC)
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参考图片Detection of Complement Component C5a R1 in J774A.1 Mouse Cell Line by Flow Cytometry. J774A.1 mouse reticulum cell sarcoma macrophage cell line was stained with Rat Anti-Mouse Complement Component C5a R1 APC‑conjugated Monoclonal Antibody (Catalog # FAB6467A, filled histogram) or isotype control antibody (Catalog # IC013A, open histogram). View our protocol for Staining Membrane-associated Proteins. |
