货号 | IC3535V-100UG |
别名 | Ecalectin; GAL9; gal-9; galectin 9; Galectin9; Galectin-9; HUAT; lectin, galactoside-binding, soluble, 9; LGALS9; LGALS9A; MGC117375; MGC125973; MGC125974; Tumor antigen HOM-HD-21; urate transporter/channel protein |
应用 | Intracellular Staining by Flow Cytometry |
目标/特异性 | Detects mouse Galectin-9 in direct ELISAs. In direct ELISAs, no cross-reactivitywith recombinant human Galectin-9 or recombinant mouse Galectin-4 is observed. |
使用方法 | Intracellular Staining by Flow Cytometry: 0.25-1 µg/106cells |
来源 | The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below. |
产品组分 |
供应商 | R&D Systems |
Entrez Gene IDs | 3965 (Human); 16859 (Mouse) |
免疫原 | E. coli-derived recombinant mouse Galectin-9 (short isoform) Ala2-Thr322 Accession # O08573-2 |
生物活性 | Mouse |
标记 | Alexa Fluor 405 |
背景 | Mouse Galectin-9 ( beta -galactoside-binding lectin 9) is a 36-39 kDa, secreted, S-type lectin. It is 353 amino acids in length and contains no identifiable signal sequence. There are two distinct carbohydrate-binding regions (aa 81-87 and 285-291) that are joined by a linker region (aa 148-205). At least one alternate splice form exists that shows a 31 aa insertion between aa 147-148. The short form is expressed on fibroblasts, hepatocytes, endothelial cells and astrocytes. The long form is expressed on intestinal epithelium. Galectin-9 binds TIM-3 on Th1 cells, inducing apoptosis. Mouse Galectin-9 is 69% and 85% aa identical to human and rat Galectin-9, respectively. |
运输条件 | Blue Ice |
存放说明 | 4℃ |
参考文献 |
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