| 货号 | FAB8447N-100UG |
| 别名 | IBD14; interferon regulatory factor 5; IRF5; IRF-5; SLEB10 | 全称 | Interferon Regulatory Factor 5 |
| 应用 | Intracellular Staining by Flow Cytometry |
| 目标/特异性 | Detects mouse IRF5 in direct ELISAs. |
| 使用方法 | Intracellular Staining by Flow Cytometry: 0.25-1 µg/106cells |
| 来源 | The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below. |
| 产品组分 |
| 供应商 | R&D Systems |
| Entrez Gene IDs | 3663 (Human); 27056 (Mouse); 296953 (Rat) |
| 纯化方式 | Protein A or G purified from hybridoma culture supernatant |
| 免疫原 | E. coli-derived recombinant mouse IRF5 Ala208-Phe288 Accession # P56477 |
| 生物活性 | Mouse |
| 标记 | Alexa Fluor 700 |
| 背景 | IRF5 is a member of the IRF family of transcription factors, a family characterized by a helix-turn-helix DNA binding domain enriched in tryptophan repeats. IRF family members show diverse cellular regulation of interferon-stimulated gene transcription, viral-mediated gene activation, apoptosis, differentiation, and cellular growth. IRF5, along with IRF7, are the key mediators of TLR signaling. IRF5 forms heterodimers with IRF3 both of which are necessary for interferon gene transcription. IRF5 knock out mice indicate that IRF5 is critical for induction of apoptosis. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 参考文献 |
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