货号 | FAB83771T-100UG |
简介 | Recombinant Monoclonal Antibody |
别名 | hematopoietically expressed homeobox; Hex; HEXHMPH; HHEX; HMPH; Homeobox protein HEX; Homeobox protein PRH; HOX11L-PEN; PRH; PRHhematopoietically-expressed homeobox protein HHEX; PRHX; PRHXhomeobox, hematopoietically expressed; proline-rich homeodomain-containing transcription factor | 全称 | Hematopoietically Expressed Homeobox |
应用 | Flow Cytometry |
目标/特异性 | Detects human HHEX in direct ELISAs and Western blots. |
使用方法 | Flow Cytometry: 0.25-1 µg/106cells |
来源 | Store the unopened product at 2 - 8 °C. Do not use past expiration date. |
产品组分 |
供应商 | R&D Systems |
Entrez Gene IDs | 3087 (Human); 15242 (Mouse); 79237 (Rat) |
免疫原 | E. coli-derived recombinant human HHEX Thr111-Gly270 Accession # Q6UX06 |
生物活性 | Human, Mouse, Rat |
标记 | Alexa Fluor 594 |
背景 | Hematopoietically-expressed homeobox protein (HHEX), also known as HEX, PRH and PRHX, is a 35-40 kDa member of the Homeobox family of transcription factors. Family members are distinguished by an evolutionarily conserved DNA-binding homeodomain of 60 amino acids (aa), which for HHEX spans aa 137-196. Human HHEX was initially isolated from hematopoietic tissue, and is present in several hematopoietic progenitors, where its expression is down-regulated during terminal cell differentiation. HHEX is also expressed in the anterior visceral endoderm during early mouse development, and in some adult tissues of endodermal origin, including liver, lung and thyroid. HHEX knockout in mice is embryonic lethal, with impaired forebrain, liver and thyroid development. Human HHEX is 270 aa in length, and over aa 111-270, shares 93% and 95% identity with mouse and rat HHEX, respectively. |
运输条件 | Blue Ice |
存放说明 | 4℃ |
参考文献 |
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