| 货号 | FAB7297S-100UG |
| 别名 | CD3d; delta polypeptide; T cell receptor gamma locus; T3D; T-cell antigen receptor, gamma polypeptide; T-cell rearranging gene, gamma; T-cell receptor, gamma cluster; TCR gamma/delta; TCRG; TiT3; TRG |
| 应用 | Flow Cytometry |
| 目标/特异性 | Detects mouse TCR gamma /δ. |
| 使用方法 | Flow Cytometry: 0.25-1 µg/106cells |
| 来源 | The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below. |
| 产品组分 |
| 供应商 | R&D Systems |
| Entrez Gene IDs | 915 (Human); 12500 (Mouse); 25710 (Rat) |
| 免疫原 | Mouse intraepithelial lymphocytes |
| 生物活性 | Mouse |
| 标记 | Alexa Fluor 750 |
| 背景 | The gamma δT-cell receptor (TCR) is a heteromer that includes type I transmembrane CD3 gamma and CD3δ glycoprotein subunits of the Igsuperfamily. T gamma δ cells develop as a minorpopulation in the thymus and migrate mainly to in skin and intestinalepithelial layers. Mouse and rat CD3 gamma andCD3δ are synthesized as 182 and 173 aminoacid (aa) precursors that result in 160 and 152 aa mature proteins with 94 and84 aa extracellular domains (ECD), respectively. The germline ECD sequences ofCD3 gamma and CD3δshare 71% and 76% aa identity between mouse and rat, respectively, while bothproteins and species share 57-62% aa identity with human CD3 gamma and CD3δ. Mouse intraepithelial lymphocytes from the small intestine, which contain a major population of gamma δ T cells, were used as the immunogen for the GL-3/5E11 antibody(1). |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 参考文献 |
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