Mouse CX3CR1 Alexa Fluor 488 Affinity Purified PAb (100 TESTS)【科瑞奥博】

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Mouse CX3CR1 Alexa Fluor 488 Affinity Purified PAb (100 TESTS)

货号： FAB5825G-100 基本售价： 4659.8 元规格： 100 Tests

产品信息

概述
货号	FAB5825G-100
别名	Beta chemokine receptor-like 1; CCRL1; chemokine (C-C) receptor-like 1; chemokine (C-X3-C motif) receptor 1; chemokine (C-X3-C) receptor 1; CMKbRL1; CMK-BRL1; CMK-BRL-1; CMKDR1; CX3C chemokine receptor 1; Fractalkine receptor; G protein-coupled receptor 13; GPR13G-protein coupled receptor 13; GPRV28; V28; V28C-X3-C CKR-1
全称	CX3C Chemokine Receptor 1
反应种属	Mouse
应用	Flow Cytometry(5 µL/10⁶cells)
目标/特异性	Detects human and mouse CX3CR1 in direct ELISAs and Western blots.
使用方法	Flow Cytometry: 5 µL/10⁶cells
来源	The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
产品组分

性能
供应商	R&D Systems
Entrez Gene IDs	1524 (Human); 13051 (Mouse); 171056 (Rat)
应用文献
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions. Atorvastatin improves plaque stability in ApoE-knockout mice by regulating chemokines and chemokine receptors. Authors: Nie P, Li D, Hu L, Jin S, Yu Y, Cai Z, Shao Q, Shen J, Yi J, Xiao H, Shen L, He B PLoS ONE, 2014;9(5):e97009. Species: Mouse Sample Type: Whole Cells Application: Flow
纯化方式	Antigen Affinity-purified
免疫原	E. coli-derived recombinant mouse CX3CR1 Met1-Thr32, Leu92-Lys104, Thr169-Val196, Lys258-Leu274 Accession # Q9Z0D9
生物活性	Mouse
标记	Alexa Fluor 488
背景	CX3CR1 (CX₃C chemokine receptor 1; also fractalkine receptor, GPCR13 and V28) is a 40 kDa member of the δ-group of rhodopsin GPCRs. It is expressed on astrocytes, microglia, macrophages, Th1 and Tc1 T cells, NK cells, mouse Gr1^lo monocytes plus smooth muscle and mast cells. CX₃CR1 mediates adhesion to fractalkine, promotes avid binding of integrins to their ligands, and extends the life of monocytes. Mouse CX3CR1 is a 7-transmembrane protein that is 354 amino acids (aa) in length. It contains a 32 aa N-terminal extracellular region that shows no glycosylation, and a 56 aa C-terminal cytoplasmic domain. Over aa 1‑32, 91‑104, 169‑196 and 258‑274 collectively, mouse CX₃CR1 shares 96% and 77% aa identity with rat and human CX₃CR1, respectively.
运输条件	Blue Ice
存放说明	4℃
参考文献	Cancer Stem Cell Markers Chemokine Nomenclature Chemokine Receptors Chemokines and Receptors Chemokines and Receptors in Allergy and Asthma Chemokines and Receptors in Angiogenesis Conventional/Classical Dendritic Cells Glomerulonephritis: Beyond Inflammation Mini-review: Chemokines III Monocyte Markers Mouse Tissue-Resident Macrophage Markers Neutrophils Renal Markers T Cell Migration/Adhesion

参考图片

Detection of CX3CR1 in Mouse Splenocytes by Flow Cytometry. Mouse splenocytes were stained with Hamster Anti-Mouse CD11c PE‑conjugated Monoclonal Antibody (Catalog # FAB69501P) and either (A) Goat Anti-Mouse CX3CR1 Alexa Fluor® 488‑conjugated Antigen Affinity-purified Polyclonal Antibody (Catalog # FAB5825G) or (B) Normal Goat IgG Alexa Fluor 488 Control (Catalog # IC108G). View our protocol for Staining Membrane-associated Proteins.