Mouse CCR1 Phycoerythrin MAb (Clone 643854) (100 TESTS)【科瑞奥博】

产品中心

当前位置：首页>产品中心

Mouse CCR1 Phycoerythrin MAb (Clone 643854) (100 TESTS)

货号： FAB5986P-100 基本售价： 4659.8 元规格： 100 Tests

产品信息

概述
货号	FAB5986P-100
别名	C-C chemokine receptor type 1; CC-CKR-1; CCR1; CCR-1; CD191 antigen; CD191; chemokine (C-C motif) receptor 1; CKR1; CKR-1; CMKBR1SCYAR1; CMKR1; HM145C-C CKR-1; LD78 receptor; Macrophage inflammatory protein 1-alpha receptor; MIP-1alpha-R; MIP1aR; RANTES receptor; RANTES-R
反应种属	Mouse
应用	Flow Cytometry(10 µL/10⁶cells)
目标/特异性	Detects mouse CCR1 in direct ELISAs and Western blots. In direct ELISAs and Western blots, nocross-reactivity with recombinant mouse CCR4, 5, or 8 is observed.
使用方法	Flow Cytometry: 10 µL/10⁶cells
来源	The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
产品组分

性能
供应商	R&D Systems
Entrez Gene IDs	1230 (Human); 12768 (Mouse); 57301 (Rat)
应用文献
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions. The generation of macrophages with anti-inflammatory activity in the absence of STAT6 signaling. Authors: Fleming B, Chandrasekaran P, Dillon L, Dalby E, Suresh R, Sarkar A, El-Sayed N, Mosser D J Leukoc Biol, 2015;98(3):395-407. Species: Mouse Sample Type: Whole Cells Application: Flow
纯化方式	Protein A or G purified from hybridoma culture supernatant
免疫原	E. coli-derived recombinant mouse CCR1 Extracellular regions (aa 1-34, aa 92-107, aa 172-192, aa 265-281) Accession # P51675
生物活性	Mouse
标记	Phycoerythrin
背景	CCR1 (C-C chemokine receptor 1; also MIP-1a receptor and CD191) is a 43 kDa member of the GPCR #1 family of transmembrane proteins. Mouse CCR1 is expressed on osteoclasts, IL-13⁺ T cells, neutrophils, bone marrow-derived mast cells, eosinophils, monocytes and vascular intimal smooth muscle cells. Multiple chemokines are reported to bind to CCR1. MIP-1a/CCL3 and RANTES/CCL5 are natural ligands, while CCL15, CCL9 and CCL23 are potent angonists after N-terminal processing. Mouse CCR1 is a 7-transmembrane protein that is 355 amino acids (aa) in length. It contains a 34 aa N-terminal extracellular domain plus a 50 aa C-terminal cytoplasmic tail. Over aa sequences 1-34, 92-107, 172-192 and 265-281 collectively, mouse CCR1 shares 76% and 89% aa identity with human and rat CCR1, respectively.
运输条件	Blue Ice
存放说明	4℃
参考文献	CC Chemokines and Receptors Chemokine Receptors Chemokines and Receptors in Allergy and Asthma Chemokines and Receptors in Angiogenesis Human CD Marker Products Monocyte Markers Multiple Myeloma Receptors in the Jak/STAT Pathway T Cell Migration/Adhesion Th1 Cells

参考图片

Detection of CCR1 in RAW 264.7 Mouse Cell Line by Flow Cytometry. RAW 264.7 mouse monocyte/macrophage cell line was stained with Rat Anti-Mouse CCR1 PE-conjugated Monoclonal Antibody (Catalog # FAB5986P, filled histogram) or isotype control antibody (Catalog # IC013P, open histogram). View our protocol for Staining Membrane-associated Proteins.

Detection of CCR1 in L1.2 Mouse Cell Line Transfected with Mouse CCR1 and eGFP by Flow Cytometry. L1.2 mouse pro-B cell line transfected with mouse CCR1 and eGFP was stained with Rat Anti-Mouse CCR1 PE‑conjugated Monoclonal Antibody (Catalog # FAB5986P). Quadrant markers were set based on control antibody staining (Catalog # IC013P). View our protocol for Staining Membrane-associated Proteins.