货号 | FAB2787A |
别名 | antigen identified by monoclonal J143; CD49 antigen-like family member C; CD49c antigen; CD49c; FLJ34631; FLJ34704; FRP-2; Galactoprotein B3; GAP-B3; GAPB3CD49C; integrin alpha-3; integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor); ITGA3; MSK18; VCA-2; very late activation protein 3 receptor, alpha-3 subunit; VL3A; VLA-3 subunit alpha; VLA3a |
反应种属 | Mouse |
应用 | Flow Cytometry(10 µL/106cells) |
目标/特异性 | Detects mouse Integrin alpha 3/CD49c in direct ELISAs and Western blots. In direct ELISAs and Western blots, less than 1% cross-reactivity with recombinat mouse (rm) Integrin alpha 2, rmIntegrin alpha 4, rmIntegrin alpha 5, rmIntegrin alpha E, rmIntegrin alpha M, rmIntegrin alpha V and rmIntegrin alpha X is observed. |
使用方法 | Flow Cytometry: 10 µL/106cells |
来源 | The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below. |
产品组分 |
供应商 | R&D Systems |
Entrez Gene IDs | 3675 (Human); 16400 (Mouse) |
纯化方式 | Antigen Affinity-purified |
免疫原 | S. frugiperda insect ovarian cell line Sf 21-derived recombinant mouse Integrin alpha 3/CD49c Phe33-Glu993 Accession # Q62470 |
生物活性 | Mouse |
标记 | Allophycocyanin |
背景 | Integrin alpha 3, also known as CD49c and VLA-3 alpha, is a type I membraneprotein that heterodimerizes with Integrin beta 1. alpha 3 beta 1 is a cell surfaceadhesion molecule that functions as a receptor for laminin,fibronectin, collagen, epiligrin, thrombospondin and chondroitinsulfate proteoglycan 4. The extracellular domain of human and mouseIntegrin alpha 3 share approximately 87% amino acid sequence homology. |
运输条件 | Blue Ice |
存放说明 | 4℃ |
参考文献 |
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Detection of Integrin alpha 3/CD49c in XB2 Mouse Cell Line by Flow Cytometry. XB2 mouse teratoma keratinocyte cell line was stained with Goat Anti-Mouse Integrin alpha 3/CD49c APC‑conjugated Antigen Affinity-purified Polyclonal Antibody (Catalog # FAB2787A, filled histogram) or isotype control antibody (Catalog # IC108A, open histogram). View our protocol for Staining Membrane-associated Proteins. |