概述| 货号 | FAB7610G |
| 别名 | CHEMERINR; chemokine receptor-like 1; chemokine-like receptor 1; CHEMR23; cmklr1; Dez; Gpcr27; G-protein coupled receptor ChemR23; G-protein coupled receptor DEZ; MGC126105; MGC126106; orphan G-protein coupled receptor, Dez |
全称 | Chemokine-like Receptor 1/Orphan G Protein-coupled Receptor ChemR23 | | 反应种属 | Mouse |
| 应用 | Flow Cytometry(5 µL/106cells)
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| 目标/特异性 | Detects mouse ChemR23 in flow cytometry. |
| 使用方法 | Flow Cytometry: 5 µL/106cells
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| 来源 | The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below. |
| 产品组分 | |
性能| 供应商 | R&D Systems |
| Entrez Gene IDs | 1240 (Human); 14747 (Mouse); 60669 (Rat) |
| 纯化方式 | Protein A or G purified from hybridoma culture supernatant |
| 免疫原 | NS0 mouse myeloma cell line transfected with mouse ChemR23 |
| 生物活性 | Mouse |
| 标记 | Alexa Fluor 488 |
| 背景 | ChemR23 is a chemoattractant receptor expressed on dendritic cells and inflammatory M1 macrophages. ChemR23 binds Chemerin and Resolvin E1 (a lipid mediator), and promotes inflammation resolution. ChemR23 also functions as a coreceptor for SIV and some primary HIV-1 strains (1,2). Mouse and human ChemR23 share 80% amino acid sequence identity. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 参考文献 | - Samson, M. et al. (1998) Eur. J. Immunol. 28:1689.
- Herova, M. et al. (2015) J. Immunol. 194:2330.
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参考图片 Detection of ChemR23 in RAW 264.7 Mouse Cell Line by Flow Cytometry. RAW 264.7 mouse monocyte/macrophage cell line was stained with Rat Anti-Mouse ChemR23 Alexa Fluor® 488‑conjugated Monoclonal Antibody (Catalog # FAB7610G, filled histogram) or isotype control antibody (Catalog # IC013G, open histogram). View our protocol for Staining Membrane-associated Proteins. |
