Mouse CCR2 Fluorescein MAb (Clone 475301) (100 TESTS)【科瑞奥博】

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Mouse CCR2 Fluorescein MAb (Clone 475301) (100 TESTS)

货号： FAB5538F-100 基本售价： 4382.2 元规格： 100 Tests

产品信息

概述
货号	FAB5538F-100
别名	C-C chemokine receptor type 2; C-C CKR-2; CC-CKR-2CKR2B; CCR2; CCR-2; CCR2A; CCR2B; CD192 antigen; CD192; chemokine (C-C motif) receptor 2; CKR2; CKR2A; CMKBR2MGC111760; FLJ78302; MCP-1 receptor; MCP-1-RMGC103828; MGC168006; Monocyte chemoattractant protein 1 receptor; monocyte chemotactic protein 1 receptor
反应种属	Mouse/Rat
应用	Flow Cytometry(10 µL/10⁶cells)
目标/特异性	Detects mouse CCR2 transfectants but not the parental cell line in flow cytometry. Does not detect HEK293 human embryonic kidney cell line transfected with mouse CCR5 in flow cytometry.
使用方法	Flow Cytometry: 10 µL/10⁶cells
来源	The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
产品组分

性能
供应商	R&D Systems
Entrez Gene IDs	729230 (Human); 12772 (Mouse); 60463 (Rat)
应用文献
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions. Innate Allorecognition Results in Rapid Accumulation of Monocyte-Derived Dendritic Cells J Immunol, 2016;0(0):. Species: Mouse Sample Type: Whole Cells Application: Flow Monocyte-Derived Macrophages Contribute to Spontaneous Long-Term Functional Recovery after Stroke in Mice Authors: S Wattananit, D Tornero, N Graubardt, T Memanishvi, E Monni, J Tatarishvi, G Miskinyte, R Ge, H Ahlenius, O Lindvall, M Schwartz, Z Kokaia J Neurosci, 2016;36(15):4182-95. Species: Mouse Sample Type: Whole Cells Application: Flow Differential TGF-beta Signaling in Glial Subsets Underlies IL-6-Mediated Epileptogenesis in Mice. Authors: Levy N, Milikovsky D, Baranauskas G, Vinogradov E, David Y, Ketzef M, Abutbul S, Weissberg I, Kamintsky L, Fleidervish I, Friedman A, Monsonego A J Immunol, 2015;195(4):1713-22. Species: Mouse Sample Type: Whole Cells Application: Flow Cessation of CCL2 inhibition accelerates breast cancer metastasis by promoting angiogenesis. Authors: Bonapace L, Coissieux M, Wyckoff J, Mertz K, Varga Z, Junt T, Bentires-Alj M Nature, 2015;515(7525):130-3. Species: Mouse Sample Type: Whole Cells Application: Flow Combined effect of insulin-like growth factor-1 and CC chemokine ligand 2 on angiogenic events in endothelial cells. Authors: Viana I, de Almeida M, Lins M, dos Santos Reis M, de Araujo Vieira L, Smaniotto S PLoS ONE, 2015;10(4):e0121249. Species: Mouse Sample Type: Whole Cells Application: Flow Myeloid-derived suppressor cells contribute to Staphylococcus aureus orthopedic biofilm infection. Authors: Heim, Cortney, Vidlak, Debbie, Scherr, Tyler D, Kozel, Jessica, Holzapfel, Melissa, Muirhead, David E, Kielian, Tammy J Immunol, 2014;192(8):3778-92. Species: Mouse Sample Type: Whole Cells Application: Flow
纯化方式	Protein A or G purified from hybridoma culture supernatant
免疫原	L1.2 mouse pro-B cell line transfected with mouse CCR2
生物活性	Mouse
标记	Fluorescein
背景	CCR2, also known as CD192, is a 38 kDa 7TM chemokine receptor that preferentially binds CCL2, CCL7, and CCL13. CCR2 is expressed by multiple hematopoietic cells, endothelial cells, fibroblasts, neurons, and smooth muscle cells. It functions as an HIV fusion co-factor and facilitates T cell recruitment during inflammation. Two alternate splice forms (CCR2A and CCR2B) differ only by the addition of 14 amino acids to the intracellular carboxyl terminal. Mouse CCR2 shares 67% and 95% aa sequence identity with human and rat CCR2, respectively.
运输条件	Blue Ice
存放说明	4℃
参考文献	CC Chemokines and Receptors Chemokine Receptors Chemokines and Receptors in Allergy and Asthma Chemokines and Receptors in Angiogenesis Human CD Marker Products Macrophage Activation Markers Monocyte Markers Myeloid Lineage Markers Myeloid-derived Suppressor Cells (MDSC) Neuroinflammation Proinflammatory Cytokines & CCR2 Promote Estrogen-deficient Bone Loss Receptors in the Jak/STAT Pathway Regulatory T Cells (Tregs) T Cell Migration/Adhesion

参考图片

Detection of CCR2 in Mouse Splenocytes byFlow Cytometry. Mouse splenocytes were stained with RatAnti-Mouse CCR2 Fluorescein‑conjugated Monoclonal Antibody (Catalog# FAB5538F) and Rat Anti-Mouse Gr‑1/Ly‑6GPE‑conjugated Monoclonal Antibody (Catalog # FAB1037P).View our protocol for StainingMembrane-associated Proteins.