| 货号 | FAB6518N-100UG |
| 别名 | CD34 antigenhematopoietic progenitor cell antigen CD34; CD34 molecule; CD34; HPCA1 |
| 应用 | Flow Cytometry |
| 目标/特异性 | Detects mouse CD34 in direct ELISAs. In direct ELISAs, nocross-reactivity with recombinant human, rat, or porcine CD34 is observed. |
| 使用方法 | Flow Cytometry: 0.25-1 µg/106cells |
| 来源 | The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below. |
| 产品组分 |
| 供应商 | R&D Systems |
| Entrez Gene IDs | 947 (Human); 12490 (Mouse); 305081 (Rat); 397160 (Porcine); 415130 (Canine) |
| 免疫原 | Mouse myeloma cell line NS0-derived recombinant mouse CD34 Thr35-Thr287 Accession # Q64314 |
| 生物活性 | Mouse |
| 标记 | Alexa Fluor 700 |
| 背景 | CD34 is a 100-105 kDa member of the CD34/podocalyxin family of molecules. It is a sialomucin type glycoprotein, and presents carbohydrate to selectins during cell migration. CD34 is found on mast cells, eosinophils, vascular endothelial cells, CD34+ stem cells and renal mesangial cells. Mature mouse CD34 is a 348 amino acid (aa) type I transmembrane protein (aa 35-382). It contains a 253 aa extracellular region (aa 35-287), and a 74 aa cytoplasmic domain that undergoes Tyr phosphorylation. There is one 90 kDa splice variant that shows a four aa substitution for aa 322-382. Mouse CD34 also is likely to undergo membrane cleavage that will generate a 54 kDa soluble form. Over aa 35-287, mouse CD34 shares 57% and 82% aa identity with human and rat CD34, respectively. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 参考文献 |
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