货号 | IC3487S-100UG |
简介 | Recombinant Monoclonal Antibody |
别名 | B cell specific activator protein; B-cell-specific transcription factor; BSAP; BSAPB-cell lineage specific activator; paired box 5; paired box gene 5 (B-cell lineage specific activator protein); paired box gene 5 (B-cell lineage specific activator); paired box homeotic gene 5; paired box protein Pax-5; Pax5; transcription factor PAX 5 | 全称 | Paired Box Gene 5/B-cell Specific Activator Protein |
应用 | Intracellular Staining by Flow Cytometry |
目标/特异性 | Detects human Pax5 in direct ELISAs and Western blots. |
使用方法 | Intracellular Staining by Flow Cytometry: 0.25-1 µg/106cells |
来源 | Store the unopened product at 2 - 8 °C. Do not use past expiration date. |
产品组分 |
供应商 | R&D Systems |
Entrez Gene IDs | 5079 (Human); 18507 (Mouse) |
免疫原 | E. coli-derived recombinant human Pax5 Thr141-His391 Accession # Q02548 |
生物活性 | Human, Mouse |
标记 | Alexa Fluor 750 |
背景 | Pax5, also known as BSAP (B-cell-specific transcription factor) is a 42 kDa protein belonging to the paired box transcription factor family. It is a developmental regulator that is important for B-cell lineage commitment and development. Human Pax5 is a 391 amino acid (aa) protein containing the paired DNA-binding domain at the N‑terminal region. Several alternatively spliced isoforms with altered C‑terminal regions and possessing different transactivation properties have been described. All isoforms share the N‑terminal 235 aa with full-length Pax5. Human Pax5 shares 99%, 97% and 94% aa sequence identity with mouse, bovine and canine Pax5, respectively. |
运输条件 | Blue Ice |
存放说明 | 4℃ |
参考文献 |
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