货号 | FAB7089P |
别名 | CD363 antigen; CD363; CHEDG1; D1S3362; EDG1; EDG-1; EDG1edg-1; Endothelial differentiation G-protein coupled receptor 1; endothelial differentiation, sphingolipid G-protein-coupled receptor, 1; FLJ58121; S1P receptor 1; S1P receptor Edg-1; s1p1; S1P1ECGF1; S1PR1; sphingosine 1-phosphate receptor 1; sphingosine 1-phosphate receptor EDG1; Sphingosine 1-phosphate receptor Edg-1; sphingosine-1-phosphate receptor 1 | 全称 | Endothelial Differentiation Gene 1 |
反应种属 | Mouse |
应用 | Flow Cytometry(10 µL/106cells) |
目标/特异性 | Detects mouse S1P1/EDG‑1 peptide in direct ELISAs. |
使用方法 | Flow Cytometry: 10 µL/106cells |
来源 | The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below. |
产品组分 |
供应商 | R&D Systems |
Entrez Gene IDs | 1901 (Human); 13609 (Mouse) |
应用文献 | |
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions. Normal Thymocyte Egress, T Cell Trafficking, and CD4(+) T Cell Homeostasis Require Interactions between RGS Proteins and G?i2 | |
纯化方式 | Protein A or G purified from hybridoma culture supernatant |
免疫原 | Mouse S1P1/EDG‑1 synthetic peptide (T4-H28) Accession # O08530 |
生物活性 | Mouse |
标记 | Phycoerythrin |
背景 | S1P1 (sphingosine 1-phosphate receptor-1), also known as EDG-1 (endothelial differentiation, G-protein coupled receptor-1) or S1PR1 (sphingosine-1-phosphate receptor 1) is a widely expressed, 37-40kDa, G protein coupled receptor within the S1P subfamily of the EDG family. S1P1is one of five receptors for the bioactive lipid S1P and mediates most of S1Peffects on angiogenesis, vascular maturation, and cell migration, especially Tcell egress from lymphoid organs. Human and mouse S1P1 share 84% amino acididentity within the N-terminal extracellular portion used as an immunogen. |
运输条件 | Blue Ice |
存放说明 | 4℃ |
参考文献 |
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Detection of S1P1/EDG‑1 in HEK293 Human Cell Line Transfected with Mouse S1P1/EDG-1 and eGFP by Flow Cytometry. HEK293 human embryonic kidney cell line transfected with mouse S1P1/EDG-1 and eGFP was stained with either (A) Rat Anti-Mouse S1P1/EDG‑1 PE‑conjugated Monoclonal Antibody (Catalog # FAB7089P) or (B) Rat IgG2A Phycoerythrin Isotype Control (Catalog # IC006P). View our protocol for Staining Membrane-associated Proteins. | |
Detection of S1P1/EDG‑1 in Mouse Thymocytes by Flow Cytometry. Mouse thymocytes were stained with Rat Anti-Mouse CD4 APC‑conjugated Monoclonal Antibody (Catalog # FAB554A) and either (A) Rat Anti-Mouse S1P1/EDG‑1 PE‑conjugated Monoclonal Antibody (Catalog # FAB7089P) or (B) Rat IgG2A Phycoerythrin Isotype Control (Catalog # IC006P). View our protocol for Staining Membrane-associated Proteins. |