| 货号 | IC8888G-100UG |
| 简介 | Recombinant Monoclonal Antibody |
| 别名 | E4BP4; E4BP4IL3BP1; IL3BP1; Interleukin-3 promoter transcriptional activator; Interleukin-3-binding protein 1; NFIL3; NF-IL3A; NFIL3AE4 promoter-binding protein 4; nuclear factor interleukin 3 regulated protein; nuclear factor interleukin-3-regulated protein; nuclear factor, interleukin 3 regulated; Transcriptional activator NF-IL3A | 全称 | Nuclear Factor, Interleukin 3 Regulated |
| 应用 | Intracellular Staining by Flow Cytometry |
| 目标/特异性 | Detects NFIL3/E4BP4 in direct ELISAs. |
| 使用方法 | Intracellular Staining by Flow Cytometry: 0.25-1 µg/106cells |
| 来源 | Store the unopened product at 2 - 8 °C. Do not use past expiration date. |
| 产品组分 |
| 供应商 | R&D Systems |
| Entrez Gene IDs | 4783 (Human); 18030 (Mouse); 114519 (Rat) |
| 免疫原 | E. coli-derived recombinant mouse NFIL3/E4BP4 Lys140-Arg462 Accession # O08750 |
| 生物活性 | Mouse |
| 标记 | Alexa Fluor 488 |
| 背景 | NFIL3 (Nuclear Factor, Interleukin 3 Regulated), also called E4BP4 (adenovirus E4 promoter binding protein 4), is an approximately 58 kDa transcription factor of the bZIP (basic leucine zipper) family. It is a transcriptional regulator expressed in T and pro-B lymphocytes and cardiomyocytes, binds IL-3 and promoters as a homodimer, and enhances cell survival. NFIL3 has also been shown to be involved in the development of Innate Lymphoid Cells (ILCs; 1,2). The 462 amino acid (aa) human NFIL3 contains a basic DNA binding domain (aa 73-95), a leucine zipper (aa 96-124), and a transcriptional repression domain (aa 299-363) that is potentially regulated by phosphorylation at Ser301 and Ser353. Within the region used as an immunogen, human NFIL3 shares 83% aa sequence identity with mouse and rat NFIL3. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 参考文献 |
|