| 货号 | FAB4464S-100UG |
| 别名 | ATPDase; CD39 antigen-like 3; CD39L3; CD39L3EC 3.6.1.5; CD39-like 3; EC 3.6.1; Ecto-apyrase 3; Ecto-ATP diphosphohydrolase 3; Ecto-ATPase 3; Ecto-ATPDase 3; ectonucleoside triphosphate diphosphohydrolase 3; ENTPD3; FLJ93839; HB6; HB6NTPDase 3; NTPDase-3 | 全称 | Ecto-Nucleoside Triphosphate Diphosphohydrolase 3 |
| 应用 | Flow Cytometry |
| 目标/特异性 | Detects mouse CD39L3/ENTPD3 in direct ELISAs. In Western blots, less than 15% cross-reactivity with recombinant human (rh) CD39L4 and no cross-reactivity with rhCD39L3, recombinant mouse (rm) CD39, or rmCD39L2 is observed. |
| 使用方法 | Flow Cytometry: 0.25-1 µg/106cells |
| 来源 | The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below. |
| 产品组分 |
| 供应商 | R&D Systems |
| Entrez Gene IDs | 956 (Human); 215446 (Mouse); 316077 (Rat) |
| 免疫原 | Chinese hamster ovary cell line CHO-derived recombinant mouse CD39L3/ENTPD3 Gln44-Pro485 Accession # NP_848791 |
| 生物活性 | Mouse |
| 标记 | Alexa Fluor 750 |
| 背景 | Ectonucleoside triphosphate diphosphohydrolase-3 (NTPDase-3) is an integral membrane protein with an extracellular catalytic domain (1). rhNTPDase-3 was expressed as a protein lacking its N- and C-terminal transmembrane domains, resulting in the secretion of the soluble rhNTPDase-3 ectodomain. NTPDase-3 hydrolyzes the beta - and gamma -phosphate groups of nucleotides, preferring ATP, ADP, UTP, and UDP as substrates (1). Through its hydrolysis of extracellular nuceotides, NTPDase-3 is important for the regulation of purinergic signaling (2). The enzyme is expressed at its highest levels in brain, pancreas, spleen, and prostate tissues (3). In the brain, NTPDase-3 may play a role in the regulation of feeding, sleep, and other behaviors (4). |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 参考文献 |
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