| 货号 | IC4704V-100UG |
| 别名 | EC 3.5.1.28; peptidoglycan recognition protein 2tagl-beta; peptidoglycan recognition protein L; PGLYRP2; PGLYRPL; PGLYRPLHMFT0141; PGRP2; PGRPL; PGRP-L; PGRP-LN-acetylmuramoyl-L-alanine amidase; PGRPLPeptidoglycan recognition protein long; TAGL; tagL-alpha; TAGL-like | 全称 | Peptidoglycan Recognition Protein Long/Peptidoglycan Recognition Protein 2 |
| 应用 | Intracellular Staining by Flow Cytometry |
| 目标/特异性 | Detects mouse PGLYRP2/PGRP-L in direct ELISAs and Western blots. In Western blots, no cross-reactivity with recombinant mouse (rm) PGRP-S and rmPGRP-1 beta is observed. |
| 使用方法 | Intracellular Staining by Flow Cytometry: 0.25-1 µg/106cells |
| 来源 | The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below. |
| 产品组分 |
| 供应商 | R&D Systems |
| Entrez Gene IDs | 114770 (Human); 57757 (Mouse) |
| 免疫原 | Mouse myeloma cell line NS0-derived recombinant mouse PGLYRP2/PGRP-L Ser23-Asn530 Accession # Q8VCS0 |
| 生物活性 | Mouse |
| 标记 | Alexa Fluor 405 |
| 背景 | PGRP-L (peptidoglycan recognition protein‑long; also called PGRP-2 or TagL) is a 530 amino acid (aa) member of the PGRP family that is expressed in the liver. All mouse PGRPs bind peptidoglycan and Gram-positive bacteria, and may function as innate immunity pattern recognition molecules. PGRP-L is a Zn2+-dependent N‑acetylmuramoyl-L-alanine amidase that hydrolyzes cell wall glycopeptides. It contains two membrane-spanning segments, with both termini thought to be extracellular, but is also reported in serum. A truncated 450 aa isoform has been reported. Overall aa identity between mouse and human PGRP-L is 68%. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |