货号 | IC2506V-100UG |
别名 | EC 2.7.11; EC 2.7.11.26; glycogen synthase kinase 3 beta; glycogen synthase kinase-3 beta; GSK3 beta; GSK-3 beta; GSK3B; GSK3beta isoform | 全称 | Glycogen Synthase Kinase 3 beta |
应用 | Intracellular Staining by Flow Cytometry |
目标/特异性 | Detects human, mouse, and rat GSK-3 beta in ELISAs and Western blots. Does not cross-react with recombinant human GSK-3 alpha. |
使用方法 | Intracellular Staining by Flow Cytometry: 0.25-1 µg/106cells |
来源 | The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below. |
产品组分 |
供应商 | R&D Systems |
Entrez Gene IDs | 2932 (Human); 56637 (Mouse); 84027 (Rat) |
免疫原 | E. coli-derived recombinant human GSK-3 beta Met1-Thr420 Accession # P49841 |
生物活性 | Human, Mouse, Rat |
标记 | Alexa Fluor 405 |
背景 | Glycogen Synthase Kinase-3 (GSK-3) is a serine/threonine kinase initially identified as an inhibitor of glycogen synthase. Two isoforms (GSK-3 alpha and GSK-3 beta ) share 85% amino acid identity. GSK-3 beta, inhibited by phosphorylation at S9 by Akt, is involved in energy metabolism, body pattern formation, and neuronal cell development. |
运输条件 | Blue Ice |
存放说明 | 4℃ |
参考文献 |
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