| 货号 | IC2256U-100UG |
| 别名 | CDKN1B; CDKN4; cyclin-dependent kinase inhibitor 1B (p27, Kip1); cyclin-dependent kinase inhibitor 1B; Cyclin-dependent kinase inhibitor p27; Kip1; KIP1P27KIP1; MEN1B; MEN4; p27; p27Kip1 | 全称 | p27 Cyclin Dependent Kinase 4 Inhibitor 1B |
| 应用 | Intracellular Staining by Flow Cytometry |
| 目标/特异性 | Detects human, mouse, and rat p27 in Western blots. |
| 使用方法 | Intracellular Staining by Flow Cytometry: 0.25-1 µg/106cells |
| 来源 | The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below. |
| 产品组分 |
| 供应商 | R&D Systems |
| Entrez Gene IDs | 1027 (Human); 12576 (Mouse); 83571 (Rat) |
| 免疫原 | E. coli-derived recombinant human p27 Met1-Thr198 Accession # P46527 |
| 生物活性 | Human, Mouse, Rat |
| 标记 | Alexa Fluor 350 |
| 背景 | The cyclin-dependent kinase (cdk) inhibitor p27/Kip1 is a tumor suppressor protein that acts in the nucleus to enforce cell cycle checkpoints. p27/Kip1 binds to and inhibits many cyclin/cdk complexes, including cyclin D/cdk4, cyclin E/cdk2, and cyclin A/cdk2. This inhibition can subsequently block progression through different phases of the cell cycle. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 参考文献 |
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