| 货号 | FAB41182G-100UG |
| 别名 | CD61 antigen; CD61; GP3A; GP3Aplatelet glycoprotein IIIa; GPIIIA; GPIIIaintegrin beta-3; INGRB3; Integrin beta 3; integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61); ITG B3; ITGB3; Platelet membrane glycoprotein IIIa |
| 应用 | Flow Cytometry |
| 目标/特异性 | Detects mouse Integrin beta 3/CD61 in direct ELISA. |
| 使用方法 | Flow Cytometry: 0.25-1 µg/106cells |
| 来源 | The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below. |
| 产品组分 |
| 供应商 | R&D Systems |
| Entrez Gene IDs | 3690 (Human); 16416 (Mouse); 29302 (Rat) |
| 免疫原 | Chinese hamster ovary cell line CHO-derived recombinant mouse Integrin alpha 2b and Integrin beta 3 linked heterodimer Leu32-Arg988 (Integrin alpha 2b) & Glu26-Asp717 (Integrin beta 3) Accession # NP_034705 (Integrin alpha 2b) & O54890 (Integrin beta 3) |
| 生物活性 | Mouse |
| 标记 | Alexa Fluor 488 |
| 背景 | Integrin beta 3 (ITGB3) is also known as platelet glycoprotein IIIa (GPIIIa) and CD61. Integrins are integral cell-surface proteins known to participate in both cell adhesion and cell-surface mediated signaling. They are composed of an alpha chain and a beta chain. ITGB3 is an integrin beta chain that forms a heterodimer with alpha-IIb or alpha-V chains. It is involved in platelet aggregation, and serves as an anchor for fibrinogen, allowing platelets to form aggregates or clots. A functional absense of ITGB3 leads to Glanzmanns thrombasthenia, a condition where platelets are activated, but fail to form an aggregate. Alternatively spliced transcripts encoding different proteins have been described, in human. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 参考文献 |
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