货号 | FAB3737S-100UG |
别名 | BMIQ9; MC3; MC3R; MC3-R; melanocortin 3 receptor; melanocortin receptor 3; Melanocortin-3 R; Melanocortin3R; Melanocortin-3R; OB20; Obesity quantitative trait locus; OQTL | 全称 | Melanocortin 3 Receptor |
应用 | Flow Cytometry |
目标/特异性 | Detects Melanocortin 3R/MC3R in direct ELISAs and Western blots. Stains mouse Melanocortin 3R/MC3R-transfected cells but not irrelevant transfectants. |
使用方法 | Flow Cytometry: 0.25-1 µg/106cells |
来源 | The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below. |
产品组分 |
供应商 | R&D Systems |
Entrez Gene IDs | 4159 (Human); 17201 (Mouse); 29310 (Rat) |
免疫原 | Y3 rat myeloid cell line transfeced with mouse Melanocortin 3R/MC3R |
生物活性 | Mouse |
标记 | Alexa Fluor 750 |
背景 | Mouse Melanocortin 3R (MC3R) is a member of the melanocortin receptor family. The 323 amino acid G-protein-coupled 7-transmembrane glycoprotein is expressed in the brain where, along with MC4R, it binds alpha, beta and gamma melanocyte stimulating hormones and is involved in regulating energy balance. MC3R is also expressed by macrophages and plays an anti-inflammatory role in the heart and other tissues. Of the 69 aa that are extracellular, mouse MC3R shares 91% and 78% sequence identity with rat and human MC3R, respectively. |
运输条件 | Blue Ice |
存放说明 | 4℃ |
参考文献 |
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