Human/Mouse/Rat CCR5 Fluorescein MAb (Clone CTC5) (100 TESTS)【科瑞奥博】

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Human/Mouse/Rat CCR5 Fluorescein MAb (Clone CTC5) (100 TESTS)

货号： FAB1802F-100 基本售价： 3668.3 元规格： 100 Tests

产品信息

概述
货号	FAB1802F-100
别名	C-C CKR-5; C-C motif chemokine receptor 5 A159A; CCCKR5; CC-CKR-5FLJ78003; CCR5; CCR-5; CD195 antigen; CD195; chemokine (C-C motif) receptor 5; chemokine receptor CCR5; chemr13; CKR5; CKR-5; HIV-1 fusion coreceptor; IDDM22CMKBR5C-C chemokine receptor type 5
反应种属	Human/Mouse/Rat
应用	Flow Cytometry(10 µL/10⁶cells)
目标/特异性	Detects human CCR5 in Western blots and human,mouse, and rat CCR5 in flow cytometry. For additional information regarding epitope specificity for this antibody and other R&D Systems anti‑human CCR5 antibodies, see Reference 1.
使用方法	Flow Cytometry: 10 µL/10⁶cells
来源	The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
产品组分

性能
供应商	R&D Systems
Entrez Gene IDs	1234 (Human); 12774 (Mouse); 117029 (Rat); 484789 (Canine); 493769 (Feline)
应用文献
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions. Interferon gamma-induced intratumoral expression of CXCL9 alters the local distribution of T cells following immunotherapy with Authors: Guirnalda P, Wood L, Goenka R, Crespo J, Paterson Y Oncoimmunology, 2013;2(8):e25752. Species: Mouse Sample Type: Whole Cells Protein kinase C and NF-kappaB-dependent CD4 downregulation in macrophages induced by T cell-derived soluble factors: consequences for HIV-1 infection. Authors: Raposo RA, Trudgian DC, Thomas B, van Wilgenburg B, Cowley SA, James W J. Immunol., 2011;187(2):748-59. Species: Human Sample Type: Whole Cells Application: Flow
纯化方式	Protein A or G purified from hybridoma culture supernatant
免疫原	CHO Chinese hamster ovary cell line transfected with human CCR5
生物活性	Human, Mouse, Rat
标记	Fluorescein
背景	CCR5 is a G protein-linked seven transmembrane domain chemokine receptor. CCR5 serves as a receptor for several chemokines including MIP-1 alpha, MIP-1 beta, MCP-2, and RANTES. It also functions as a coreceptor for Macrophage Tropic HIV-1 infection.
运输条件	Blue Ice
存放说明	4℃
参考文献	Lee, B. et al. (1999) J. Biol. Chem. 274:9617.

参考图片

Detection of CCR5 in Human PBMCs by Flow Cytometry. Human peripheral blood mononuclear cells (PBMCs) were stained with Mouse Anti-Human CD3 epsilon Alexa Fluor® 405‑conjugated Monoclonal Antibody (Catalog # FAB100V) and either (A) Mouse Anti-Human/Mouse/Rat CCR5 Fluorescein‑conjugated Monoclonal Antibody (Catalog # FAB1802F) or (B) Mouse IgG₁ Fluorescein Isotype Control (Catalog # IC002F). View our protocol for Staining Membrane-associated Proteins.

Detection of CCR5 in Mouse Splenocytes by Flow Cytometry. Mouse splenocytes treated with anti-CD3, anti-CD28, 5 ng/mL Recombinant Mouse IL‑12 (Catalog # 419-ML) and 10 μg/mL Goat Anti-Mouse IL‑4 Polyclonal Antibody (Catalog # AB-404-NA) for 3 days to induce Th1 development were stained with Mouse Anti-Human/Mouse/Rat CCR5 Fluorescein‑conjugated Monoclonal Antibody (Catalog # FAB1802F, filled histogram) or isotype control antibody (Catalog # IC002F, open histogram). View our protocol for Staining Membrane-associated Proteins.