货号 | FAB13501A |
简介 | Clone GoH3 was used by HLDA to establish CD designation |
别名 | CD49 antigen-like family member F; CD49f antigen; CD49f; DKFZp686J01244; FLJ18737; integrin alpha-6; integrin alpha6B; integrin, alpha 6; ITGA6; ITGA6B; Platelet gpl; VLA-6 |
反应种属 | Human/Bovine/Mouse |
应用 | Flow Cytometry |
目标/特异性 | Detects human, mouse, and bovine Integrin alpha 6/CD49f. Recognizes an epitope in the extracellular domain of the Integrin alpha 6 subunit. |
使用方法 | Flow Cytometry: 10 µL/106cells |
来源 | The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below. |
产品组分 |
供应商 | R&D Systems |
Entrez Gene IDs | 3655 (Human); 16403 (Mouse) |
应用文献 | |
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions. Human milk protein production in xenografts of genetically engineered bovine mammary epithelial stem cells. | |
纯化方式 | Protein A or G purified from hybridoma culture supernatant |
免疫原 | Mouse mammary tumor cells |
生物活性 | Human, Mouse, Bovine |
标记 | APC |
背景 | Integrin alpha 6 (also VLA-6, CD49F and ITA6) is a 130-150 kDa member of the Integrin alpha chain family of molecules. Mature Integrin alpha 6 is a 1107 amino acid (aa) type I transmembrane glycoprotein that contains a 1027 aa extracellular region and a 93 aa cytoplasmic tail. The ECD is cleaved to generate a disulfide-linked dimer that shows a 125 kDa heavy chain (aa 24-938), and a 30-31 kDa membrane-bound light chain (aa 942-1130). Integrin alpha 6 forms a nondisulfide-linked heterodimeric complex with both integrin beta 1 and beta 4. Each complex serves as a receptor for laminin. |
运输条件 | Blue Ice |
存放说明 | 4℃ |
参考文献 |
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Detection of Integrin alpha 6/CD49f in Human Blood Lymphocytes by Flow Cytometry. Human peripheral blood lymphocytes were stained with Rat Anti-Human/Mouse/Bovine Integrin alpha 6/CD49f APC‑conjugated Monoclonal Antibody (Catalog # FAB13501A, filled histogram) or isotype control antibody (Catalog # IC006A, open histogram). View our protocol for Staining Membrane-associated Proteins. | |
Detection of Integrin alpha 6/CD49f in Mouse Splenocytes by Flow Cytometry. Mouse splenocytes were stained with Rat Anti-Human/Mouse/Bovine Integrin alpha 6/CD49f APC‑conjugated Monoclonal Antibody (Catalog # FAB13501A) and Rat Anti-Mouse CD3 PE‑conjugated Monoclonal Antibody (Catalog # FAB4841P). Quadrant markers were set based on control antibody staining (Catalog # IC006A). View our protocol for Staining Membrane-associated Proteins. |