Mouse CD11c Alexa Fluor 488 MAb (Cl N418) (100 TESTS)
货号：
FAB69501G-100 基本售价：
3668.3 元 规格：
100 Tests
产品信息
概述| 货号 | FAB69501G-100 |
| 别名 | 95 alpha chain; 95; 95, alpha subunit; CD11 antigen-like family member C; CD11c antigen; CD11c; CD11Cleu M5, alpha subunit; Integrin alpha X; integrin alpha-X; integrin, alpha X (antigen CD11C (p150), alpha polypeptide); integrin, alpha X (complement component 3 receptor 4 subunit); ITGAX; Leu M5; Leukocyte adhesion glycoprotein p150; Leukocyte adhesion receptor p150; leukocyte surface antigen p150; myeloid membrane antigen, alpha subunit; p150 95 integrin alpha chain; p150,95 alpha; SLEB6 |
| 反应种属 | Mouse |
| 应用 | Flow Cytometry |
| 目标/特异性 | Detects mouse Integrin alpha X/CD11c.
|
| 使用方法 | Flow Cytometry: 5 µL/106cells
|
| 来源 | The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below. |
| 产品组分 | |
性能| 供应商 | R&D Systems |
| Entrez Gene IDs | 3687 (Human); 16411 (Mouse); 64350 (Rat) |
| 纯化方式 | Protein A or G purified from hybridoma culture supernatant |
| 免疫原 | Mouse spleen dendritic cells
|
| 生物活性 | Mouse |
| 标记 | Alexa Fluor 488 |
| 背景 | The Integrin alpha X subunit, also known as CD11c, is a 150 kDa type I transmembrane protein that noncovalently heterodimerizes with the beta 2 subunit (CD18) to form alpha X/ beta 2, also known as p150/p95 and complement receptor type 4 (CR4). Integrin alpha X beta 2 is expressed on macrophages, dendritic cells, CD8+ T cells, and other leukocyte subsets. The 1097 aa mouse alpha X extracellular domain shares 71% and 87% amino acid (aa) identity with human and rat alpha X, respectively. One potential alpha X isoform is truncated at aa 828. Some adhesion partners of alpha X beta 2 are shared with alpha M beta 2/CD11b:CD18 (complement iC3b, ICAMs, vWF and fibrinogen) while other adhesion partners (osteopontin, Thy-1, plasminogen, heparin) are unique. Unlike alpha M beta 2, alpha X beta 2 is not constitutively active. alpha X beta 2 adhesion mediates cell proliferation, degranulation, chemotactic migration, and phagocytosis of complement-opsonized particles. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 参考文献 | - Adhesion Molecules
- Adhesive Interactions in Allergy and Asthma
- B Cell Chemotaxis, Migration, and Adhesion
- Basophils
- Common Macrophage Markers
- Conventional/Classical Dendritic Cells
- Granulocyte Markers
- HGF/SF Activation of Integrins
- Human CD Marker Products
- Inflammatory/Monocyte-derived Dendritic Cells
- Integrin Ligands at a Glance (J. Cell. Sci.)
- Integrin Subunit Interactions
- Integrins and Associated Molecules
- Isolation, Culture, and Identification of Natural Killer Cells
- Langerhans and Dermal Dendritic Cells
- Monocyte Markers
- Mouse Tissue-Resident Macrophage Markers
- Myeloid-derived Suppressor Cells (MDSC)
- Plasmacytoid Dendritic Cells
- T Cell Migration/Adhesion
|
参考图片Detection of CD11c in Mouse Splenocytes by Flow Cytometry. Mouse splenocytes were stained with Rat Anti-Mouse MHC class II (I‑A/I‑E) APC‑conjugated Monoclonal Antibody (Catalog # FAB6118A) and either (A) Hamster Anti-Mouse CD11c Alexa Fluor® 488‑conjugated Monoclonal Antibody (Catalog # FAB69501G) or (B) Hamster IgG Alexa Fluor 488 Control. View our protocol for Staining Membrane-associated Proteins. |
