Human/Mouse/Rat STAT3 Fluorescein MAb (Clone 232209) (100 TESTS)【科瑞奥博】

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Human/Mouse/Rat STAT3 Fluorescein MAb (Clone 232209) (100 TESTS)

货号： IC1799F 基本售价： 3529.5 元规格： 100 Tests

产品信息

概述
货号	IC1799F
别名	Acute-phase response factor; APRFMGC16063; DNA-binding protein APRF; FLJ20882; HIES; signal transducer and activator of transcription 3 (acute-phase responsefactor); signal transducer and activator of transcription 3
全称	Signal Transducer and Activator of Transcription 3
反应种属	Human/Mouse/Rat
应用	Intracellular Staining by Flow Cytometry(10 µL/10⁶cells)
目标/特异性	The unconjugated antibody (Catalog # MAB1799) detects human, mouse, and rat STAT3 in Western blots.
使用方法	Intracellular Staining by Flow Cytometry: 10 µL/10⁶cells
来源	The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
产品组分

性能
供应商	R&D Systems
Entrez Gene IDs	6774 (Human); 20848 (Mouse); 25125 (Rat)
纯化方式	Protein A or G purified from hybridoma culture supernatant
免疫原	E. coli-derived recombinant human STAT3 Met1-Asn175 Accession # P40763
生物活性	Human, Mouse, Rat
标记	Fluorescein
背景	Signal Transducer and Activator of Transcription (STAT) proteins are transcription factors activated in response to cytokine, growth factor, or hormone receptor signaling. STAT3 is an 89-92 kDa, and most widely expressed, member of the STAT-family of molecules. STAT3 is considered a direct transcription factor; that is it does not act in an indirect way such as epigenetically through the regulation of DNA methylation. Activation/phosphorylation of STAT3 results in homodimerization or heterodimerization with STAT1, whereupon it enters the nucleus to principally promote cell cycle progression. The propensity of STAT3 and STAT5 toward cell division is of particular interest in oncology. Over amino acids 1-175 of STAT3 that include a protein-protein interaction domain and an NLS, human, rat and mouse show 100% amino acid sequence identity.
运输条件	Blue Ice
存放说明	4℃
参考文献	Apoptosis Transcription Factors and Regulators B Cell Markers Cancer Stem Cell Transcription Factors Chemokine Receptor Intracellular Signaling Common gamma Chain Receptor Family Dendritic Cell Development Embryonic and Induced Pluripotent Stem Cell Markers Epithelial Stem Cell Transcription Factors Focal Adhesions Gametes and Fertilization GDNF Family Hematopoietic Stem Cell Transcription Factors and Regulators ICC / IHC Images: STAT3 IL-10/Interferon Family IL-12 Family Immunoglobulin-Like Domain Transcription Factors Interactive Pathway: Th17 Differentiation Intracellular Signaling Molecules in Angiogenesis Jak and STAT Proteins Mesenchymal Stem Cell Transcription Factors Mini-review: STAT Proteins Myeloid-derived Suppressor Cells (MDSC) Neural Stem Cell Transcription Factors PDGF Family Pluripotent Stem Cell Transcription Factors Signaling Molecules and Transcriptional Regulators of Tfh Cell Differentiation STAT Th17 Cells Th22 Cells Transcription Factors in the Akt Pathway Transcriptional Regulators in Allergy and Asthma VEGF Family

参考图片

Detection of STAT3 in Jurkat Human Cell Line by Flow Cytometry. Jurkat human acute T cell leukemia cell line was stained with Mouse Anti-Human/Mouse/Rat STAT3 Fluorescein‑conjugated Monoclonal Antibody (Catalog # IC1799F, filled histogram) or isotype control antibody (Catalog # IC0041F, open histogram). View our protocol for Staining Intracellular Molecules.