货号 | FAB8628P-100 |
简介 | Recombinant Monoclonal Antibody |
别名 | CD128; CD181 antigen; CD181; CDw128aC-C; chemokine (C-X-C motif) receptor 1; CKR-1; CMKAR1; C-X-C chemokine receptor type 1; CXC-R1; CXCR-1; High affinity interleukin-8 receptor A; IL-8 receptor type 1; IL-8R A; IL8R1; IL8RA; IL8RAC-C-CKR-1; IL8RBA; interleukin 8 receptor, alpha; interleukin-8 receptor type 1; interleukin-8 receptor type A | 全称 | Interleukin 8 Receptor A |
应用 | Flow Cytometry |
目标/特异性 | Detects mouse CXCR1 transfectants but not CXCR2 transfectants in flow cytometry. |
使用方法 | Flow Cytometry: 10 µL/106cells |
来源 | The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below. |
产品组分 |
供应商 | R&D Systems |
Entrez Gene IDs | 3577 (Human); 227288 (Mouse); 54258 (Rat) |
应用文献 | |
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions. Mature dendritic cell derived from cryopreserved immature dendritic cell shows impaired homing ability and reduced anti-viral therapeutic effects | |
纯化方式 | Protein A or G purified from cell culture supernatant |
免疫原 | A peptide corresponding to the N-terminal amino acid sequence of mouse CXCR1 Accession # NP_839972 |
生物活性 | Mouse |
标记 | Phycoerythrin |
背景 | CXCR1 is a G protein-linked seven transmembrane domain spanning chemokine receptor that binds to mouse GCP-2, which is a powerful chemotactic factor. Binding of IL-8 to the receptor causes activation of neutrophils. The chemokine receptors CXCR1 and CXCR2 play an important role in mediating neutrophil recruitment and neutrophil-dependent injury in several models of inflammation. |
运输条件 | Blue Ice |
存放说明 | 4℃ |
参考文献 |
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Detection of CXCR1/IL‑8 RA in HEK293 Human Cell Line Transfected with Mouse CXCR1/IL-8 RA and eGFP by Flow Cytometry. HEK293 human embryonic kidney cell line transfected with either (A) mouse CXCR1/IL-8 RA or (B) mouse CXCR2/IL-8 RB and eGFP was stained with Rabbit Anti-Mouse CXCR1/IL‑8 RA PE‑conjugated Monoclonal Antibody (Catalog # FAB8628P). Quadrant markers were set based on control antibody staining (Catalog # IC105P). View our protocol for Staining Membrane-associated Proteins. |