Mouse CD161/NK1.1 Alexa Fluor 488 MAb (Clone 694370) (100 TESTS)【科瑞奥博】

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Mouse CD161/NK1.1 Alexa Fluor 488 MAb (Clone 694370) (100 TESTS)

货号： FAB7614G 基本售价： 3390.7 元规格： 100 Tests

产品信息

概述
货号	FAB7614G
别名	CD161 antigen; CD161; CD161c; CLEC5BC-type lectin domain family 5 member B; HNKR-P1a; killer cell lectin-like receptor subfamily B member 1; killer cell lectin-like receptor subfamily B, member 1; Klrb1c; Ly55c; Ly-59; Natural killer cell surface protein P1A; NKR-P1; NKR-P1AMGC138614; NKRP1ANKR
反应种属	Mouse
应用	Flow Cytometry(5 µL/10⁶cells)
目标/特异性	Detects mouse CD161/NK1.1 expressed specifically in the C57/B6 mouse strain. No detection of CD161/NK1.1 was observed in the BALB/c mouse strain. In direct ELISAs, less than 5% cross-reactivity with recombinant mouse (rm) KLRB-1B is observed.
使用方法	Flow Cytometry: 5 µL/10⁶cells
来源	The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
产品组分

性能
供应商	R&D Systems
Entrez Gene IDs	17059 (Mouse)
纯化方式	Protein A or G purified from hybridoma culture supernatant
免疫原	Mouse myeloma cell line NS0-derived recombinant mouse CD161/NK1.1 Val62-Ser220 Accession # P27814
生物活性	Mouse
标记	Alexa Fluor 488
背景	KLRB-1C, also known as NK1.1, CD161c, Ly-55, and NKR-P1c, is a 28 kDa type 2 transmembrane protein in the killer cell lectin-like receptor family. CD161 is expressed as a disulfide-linked homodimer on the surface of NK cells and subpopulations of NKT, CD4⁺, CD8⁺, and gamma /δ T cells. Its cross-linking on NK cells induces cytolytic activity, and on CD4 cells it promotes IgE production and the expansion of Th2 responses. Mature mouse CD161 consists of a 45 amino acid (aa) cytoplasmic domain, a 21 aa transmembrane segment, and a 157 aa extracellular domain with one C-type lectin domain.
运输条件	Blue Ice
存放说明	4℃
参考文献	C-type Lectin Family gamma delta T Cells Group 1 ILCs Group 2 ILCs Isolation, Culture, and Identification of Natural Killer Cells LTi Cells Natural Killer T (NKT) Cells NCR+ILC3 Th17 Cells

参考图片

Detection of CD161/NK1.1 in Mouse Splenocytes by Flow Cytometry. Mouse splenocytes were stained with Rat Anti-Mouse NKp46/NCR1 APC‑conjugated Monoclonal Antibody (Catalog # FAB22252A) and either (A) Rat Anti-Mouse CD161/NK1.1 Alexa Fluor® 488‑conjugated Monoclonal Antibody (Catalog # FAB7614G) or (B) Rat IgG_2A Alexa Fluor 488 Isotype Control (Catalog # IC006G). View our protocol for Staining Membrane-associated Proteins.