货号 | FAB2145F-100 |
别名 | Bonzo; BONZOG-protein coupled receptor bonzo; CD186 antigen; CD186; CDw186; chemokine (C-X-C motif) receptor 6; C-X-C chemokine receptor type 6; CXCR6; CXC-R6; CXCR-6; G protein-coupled receptor; STRL33; STRL33G-protein coupled receptor STRL33; TYMSTRCD186 |
反应种属 | Mouse |
应用 | Flow Cytometry(10 µL/106cells) |
目标/特异性 | Stains mouse CXCR6-transfected cells but not irrelevant transfectants. |
使用方法 | Flow Cytometry: 10 µL/106cells |
来源 | The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below. |
产品组分 |
供应商 | R&D Systems |
Entrez Gene IDs | 10663 (Human); 80901 (Mouse); 100124593 (Rat) |
应用文献 | |
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions. CXCL16 suppresses liver metastasis of colorectal cancer by promoting TNF-alpha-induced apoptosis by tumor-associated macrophages. | |
纯化方式 | Protein A or G purified from hybridoma culture supernatant |
免疫原 | CHO Chinese hamster ovary cell line transfected with mouse CXCR6 Met1-Leu351 Accession # Q9EQ16 |
生物活性 | Mouse |
标记 | Fluorescein |
背景 | CXCR6, also known as Bonzo and STRL33, is a G protein coupled chemokine receptor expressed on activated T cells and tumor-infiltrating lymphocytes. It binds soluble CXCL16 and membrane-anchored CXCL16 expressed on dendritic cells and macrophages. |
运输条件 | Blue Ice |
存放说明 | 4℃ |
参考文献 |
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Detection of CXCR6 in Mouse Splenocytes by Flow Cytometry. Mouse splenocytes treated with PMA and Calcium Ionomycin overnight were stained with Rat Anti-Mouse CXCR6 Fluorescein‑conjugated Monoclonal Antibody (Catalog # FAB2145F) and Rat Anti-Mouse CD3 APC‑conjugated Monoclonal Antibody (Catalog # FAB4841A). Quadrant markers were set based on control antibody staining (Catalog # IC013C). View our protocol for Staining Membrane-associated Proteins. |