Mouse 5-Nucleotidase/CD73 Fluorescein MAb (Clone 496406) (100 TESTS)【科瑞奥博】

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Mouse 5-Nucleotidase/CD73 Fluorescein MAb (Clone 496406) (100 TESTS)

货号： FAB4488F 基本售价： 2964.4 元规格： 100 Tests

产品信息

概述
货号	FAB4488F
别名	5 nucleotidase (CD73); 5-NT; 5-NT; 5-nucleotidase, ecto (CD73); CD73 antigen; CD73; E5NT; EC 3.1.3.5; ecto-5-nucleotidase; eN; eNT; NT; NT55-nucleotidase; NT5E; NTE; Purine 5-Prime-Nucleotidase
反应种属	Mouse
应用	Flow Cytometry(10 µL/10⁶cells)
目标/特异性	Detects mouse 5‑Nucleotidase/CD73 in direct ELISAs.
使用方法	Flow Cytometry: 10 µL/10⁶cells
来源	The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
产品组分

性能
供应商	R&D Systems
Entrez Gene IDs	4907 (Human); 23959 (Mouse); 58813 (Rat)
应用文献
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions. Purinergic signaling on leukocytes infiltrating the LPS-injured lung. Authors: Friebe D, Yang T, Schmidt T, Borg N, Steckel B, Ding Z, Schrader J PLoS ONE, 2014;9(4):e95382. Species: Mouse Sample Type: Whole Cells Application: Flow
纯化方式	Protein A or G purified from hybridoma culture supernatant
免疫原	Chinese hamster ovary cell line CHO-derived recombinant mouse 5‑Nucleotidase/CD73 Trp29-Lys549 Accession # Q61503
生物活性	Mouse
标记	Fluorescein
背景	CD73, an ecto-5’-Nucleotidase, is an ectoenzyme that is attached to the cell membrane by a glycosyl phophatidylinositol anchor (1, 2). The enzyme is expressed by most cell types. The 5’-Nucleotidase activity of CD73 converts extracellular nucleoside-5’-monophosphates to nucleosides. CD73 is one of several enzymes responsible for the production of extracellular adenosine, a signaling molecule that is involved in responses to inflammation and tissue injury (3).
运输条件	Blue Ice
存放说明	4℃
参考文献	Resta, R. et al. (1993) Gene 133:171. Resta, R. et al. (1998) Immunol. Rev. 161:95. Pilcher, M. et al. (2003) J. Biol. Chem. 278:13468.

参考图片

Detection of 5‑Nucleotidase/CD73 in Mouse Splenocytes by Flow Cytometry. Mouse splenocytes were stained with Rat Anti-Mouse CD3 APC‑conjugated Monoclonal Antibody (Catalog # FAB4841A) and either (A) Rat Anti-Mouse 5‑Nucleotidase/CD73 Fluorescein‑conjugated Monoclonal Antibody (Catalog # FAB4488F) or (B) Rat IgG_2A Fluorescein Isotype Control (Catalog # IC006F). View our protocol for Staining Membrane-associated Proteins.