Mouse CD38 Fluorescein Affinity Purified PAb (100 TESTS)【科瑞奥博】

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Mouse CD38 Fluorescein Affinity Purified PAb (100 TESTS)

货号： FAB4947F 基本售价： 2399.3 元规格： 100 Tests

产品信息

概述
货号	FAB4947F
别名	ADP-ribosyl cyclase 1; ADP-ribosyl Cyclase; ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase; cADPr hydrolase 1; CD38 antigen (p45); CD38 antigen; CD38 molecule; CD38; Cyclic ADP-ribose hydrolase 1; Cyclic ADP-ribose Hydrolase; EC 3.2.2.5; NAD(+) nucleosidase; T10
全称	Cluster of Differentiation 38
反应种属	Mouse
应用	Flow Cytometry(10 µL/10⁶cells)
目标/特异性	Detects mouse CD38 in direct ELISAs and Western blots. In direct ELISAs and Western blots, approximately 20% cross‑reactivity with recombinant human CD38 is observed.
使用方法	Flow Cytometry: 10 µL/10⁶cells
来源	The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
产品组分

性能
供应商	R&D Systems
Entrez Gene IDs	952 (Human); 12494 (Mouse); 25668 (Rat)
纯化方式	Antigen Affinity-purified
免疫原	Mouse myeloma cell line NS0-derived recombinant mouse CD38 Leu45-Thr304 Accession # EDL37596
生物活性	Mouse
标记	Fluorescein
背景	CD38, also known as ADP-ribosyl Cyclase and Cyclic ADP-ribose Hydrolase, is a Type II integral membrane protein. The enzyme is able to transform NAD(P)⁺ into three different products with calcium mobilizing ability; cyclic ADP-ribose, NAADP⁺, and ADP-ribose (1). CD38 is expressed in B and T lymphocytes, osteoclasts, and in cardiac, pancreatic, liver and kidney cells (2, 3). Through its production of cyclic ADP-ribose, CD38 modulates calcium-mediated signal transduction in many types of cells, including neutrophils and pancreatic beta cells (4, 5). CD38 has been shown to regulate oxytocin secretion, and may be involved in the development of complex social behaviors in mammals (6).
运输条件	Blue Ice
存放说明	4℃
参考文献	Schuber, F. and F.E. Lund (2004) Curr. Mol. Med. 4:249. Jackson, D.G. and J.I. Bell (1990) J. Immunol. 144:2811. Sun, L. et al. (1999) J. Cell Biol. 146:1161. Partida-Sanchez, S. et al. (2001) Nature Med. 7:1209. Kato, I. et al. (1995) J. Biol. Chem. 270:30045. Jin, D. et al. (2007) Nature 446:41.

参考图片

Detection of CD38 in Mouse Splenocytes by Flow Cytometry. Mouse splenocytes were stained with Sheep Anti-Mouse CD38 Fluorescein‑conjugated Antigen Affinity-purified Polyclonal Antibody (Catalog # FAB4947F, filled histogram) or isotype control antibody (Catalog # IC016F, open histogram). View our protocol for Staining Membrane-associated Proteins.