Mouse Semaphorin 4B Alexa Fluor 647 MAb (Cl 761915) (25 TESTS)【科瑞奥博】

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Mouse Semaphorin 4B Alexa Fluor 647 MAb (Cl 761915) (25 TESTS)

货号： FAB6239R-025 基本售价： 2111.7 元规格： 25 Tests

产品信息

概述
货号	FAB6239R-025
别名	KIAA1745sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and shortcytoplasmic domain, 4B; MGC131831; sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and shortcytoplasmic domain, (semaphorin) 4B; SEMA4B; SEMAC; semaphorin-4B; SemC
反应种属	Mouse
应用	Flow Cytometry
目标/特异性	Detects mouse Semaphorin 4B in direct ELISAs. Stains mouse Semaphorin 4B transfectants but not irrelevant transfectants in flow cytometry.
使用方法	Flow Cytometry: 5 µL/10⁶cells
来源	The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
产品组分

性能
供应商	R&D Systems
Entrez Gene IDs	10509 (Human); 20352 (Mouse); 293042 (Rat)
纯化方式	Protein A or G purified from hybridoma culture supernatant
免疫原	Mouse myeloma cell line NS0-derived recombinant mouse Semaphorin 4B Leu31-Glu703 Accession # NP_038687
生物活性	Mouse
标记	Alexa Fluor 647
背景	Semaphorin 4B (Sema4B; also SemaC) is a 95‑100 kDa, class IV member of the semaphorin family of proteins. It is expressed in neurons, and following PSD-95 induced clustering, participates in the formation or functioning of glutamatergic synapses. Mature mouse Sema4B is a type I transmembrane glycoprotein that is 793 amino acids (aa) in length. It contains a 673 aa extracellular region (aa 31‑703) that is characterized by one Sema domain (aa 57‑492), a PSI region (aa 512‑582), and an Ig‑like C2‑type domain (aa 589‑649). There are three phosphoserines in the cytoplasmic tail. Over aa 31‑703, mouse Sema4B shares 86% and 95% aa identity with human and rat Sema4B, respectively.
运输条件	Blue Ice
存放说明	4℃
参考文献	Axon Guidance and Neuron Migration Proteoglycans Semaphorins, Plexin Receptors, and Related Molecules

参考图片

Detection of Semaphorin 4B in HEK293 Human Cell Line Transfected with Mouse Semaphorin 4B and eGFP by Flow Cytometry. HEK293 human embryonic kidney cell line transfected with mouse Semaphorin 4B and eGFP was stained with either (A) Rat Anti-Mouse Semaphorin 4B Alexa Fluor® 647‑conjugated Monoclonal Antibody (Catalog # FAB6239R) or (B) Rat IgG_2A Alexa Fluor 647 Isotype Control (Catalog # IC006R). View our protocol for Staining Membrane-associated Proteins.