Mouse CCR2 Alexa Fluor 647 MAb (Clone 475301) (25 TESTS)
货号：
FAB5538R-025 基本售价：
1824.2 元 规格：
25 Tests
产品信息
概述| 货号 | FAB5538R-025 |
| 别名 | C-C chemokine receptor type 2; C-C CKR-2; CC-CKR-2CKR2B; CCR2; CCR-2; CCR2A; CCR2B; CD192 antigen; CD192; chemokine (C-C motif) receptor 2; CKR2; CKR2A; CMKBR2MGC111760; FLJ78302; MCP-1 receptor; MCP-1-RMGC103828; MGC168006; Monocyte chemoattractant protein 1 receptor; monocyte chemotactic protein 1 receptor |
| 反应种属 | Mouse |
| 应用 | Flow Cytometry(5 µL/106cells)
|
| 目标/特异性 | Detects mouse CCR2 transfectants but not the parental cell line in flow cytometry. Does not detect HEK293 human embryonic kidney cell line transfected with mouse CCR5 in flow cytometry. |
| 使用方法 | Flow Cytometry: 5 µL/106cells
|
| 来源 | The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below. |
| 产品组分 | |
性能| 供应商 | R&D Systems |
| Entrez Gene IDs | 729230 (Human); 12772 (Mouse); 60463 (Rat) |
| 纯化方式 | Protein A or G purified from hybridoma culture supernatant |
| 免疫原 | L1.2 mouse pro-B cell line transfected with mouse CCR2 |
| 生物活性 | Mouse |
| 标记 | Alexa Fluor 647 |
| 背景 | CCR2, also known as CD192, is a 38 kDa 7TM chemokine receptor that binds CCL2, CCL7, CCL8, CCL12 (in mouse only) and CCL13. CCR2 is expressed by multiple hematopoietic cells plus, endothelial cells, fibroblasts, and smooth muscle cells. It functions as an HIV fusion co-factor and facilitates T cell recruitment during inflammation. Mouse CCR2 shares 67% and 95% aa sequence identity with human and rat CCR2, respectively. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 参考文献 | - CC Chemokines and Receptors
- Chemokine Receptors
- Chemokines and Receptors in Allergy and Asthma
- Chemokines and Receptors in Angiogenesis
- Human CD Marker Products
- Macrophage Activation Markers
- Monocyte Markers
- Myeloid Lineage Markers
- Myeloid-derived Suppressor Cells (MDSC)
- Neuroinflammation
- Proinflammatory Cytokines & CCR2 Promote Estrogen-deficient Bone Loss
- Receptors in the Jak/STAT Pathway
- Regulatory T Cells (Tregs)
- T Cell Migration/Adhesion
|
参考图片Detection of CCR2 in Mouse Splenocytes by Flow Cytometry. Mouse splenocytes were stained with Rat Anti-Mouse Gr‑1/Ly‑6G Fluorescein‑conjugated Monoclonal Antibody (Catalog # FAB1037F) and either (A) Rat Anti-Mouse/Rat CCR2 Alexa Fluor® 647‑conjugated Monoclonal Antibody (Catalog # FAB5538R) or (B) Rat IgG 2B Alexa Fluor 647 Isotype Control (Catalog # IC013R). View our protocol for Staining Membrane-associated Proteins. |
Detection of CCR2 in NS0 Mouse Cell Line Transfected with Mouse CCR2 and eGFP by Flow Cytometry. NS0 mouse myeloma cell line transfected with mouse CCR2 and eGFP was stained with either (A) Rat Anti-Mouse/Rat CCR2 Alexa Fluor® 647‑conjugated Monoclonal Antibody (Catalog # FAB5538R) or (B) Rat IgG 2B Alexa Fluor 647 Isotype Control (Catalog # IC013R). View our protocol for Staining Membrane-associated Proteins. |
