Human/Rat CCR4 Alexa Fluor 647 MAb (Clone 205410) (25 TESTS)【科瑞奥博】

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Human/Rat CCR4 Alexa Fluor 647 MAb (Clone 205410) (25 TESTS)

货号： FAB1567R-025 基本售价： 1824.2 元规格： 25 Tests

产品信息

概述
货号	FAB1567R-025
别名	C-C chemokine receptor type 4; C-C CKR-4; CC-CKR-4HGCN:14099; CCR-4; CD194 antigen; CD194; chemokine (C-C motif) receptor 4; chemokine (C-C) receptor 4; ChemR13; CKR4MGC88293; CMKBR4k5-5; K5-5
反应种属	Human/Rat
应用	Flow Cytometry(5 µL/10⁶cells)
目标/特异性	Stains human CCR4-transfected cell lines but not the corresponding parent cell lines. Also detects human CCR4 on human PBLs and platelets and rat CCR4 on rat splenocytes.
使用方法	Flow Cytometry: 5 µL/10⁶cells
来源	The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
产品组分

性能
供应商	R&D Systems
Entrez Gene IDs	1233 (Human); 12773 (Mouse); 171054 (Rat)
应用文献
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions. Skewing towards Treg and Th2 responses is a characteristic feature of sustained remission in ANCA-positive granulomatosis with polyangiitis Authors: W Szczeklik, B Jakie?a, K Wawrzycka-, M Sanak, M Hubalewska, A Padjas, M Surmiak, K Szczeklik, J Sznajd, J Musia? Eur. J. Immunol, 2017;0(0):. Species: Human Sample Type: Whole Cells Application: Flow
纯化方式	Protein A or G purified from hybridoma culture supernatant
免疫原	Human CCR4 transfectants Met1-Leu360 Accession # P51679
生物活性	Human, Rat
标记	Alexa Fluor 647
背景	CCR4, also known as CD194, is a G protein-linked seven transmembrane domain chemokine receptor that binds the chemokines CCL17/TARC and CCL22/MDC. Current evidence suggests that CCR4 expression is associated with CLA⁺, Th-17 and Th-2 type T cells, and with CD4⁺CD30⁺ thymocytes and platelets. CCR4 expression has also been reported on mature dendritic cells.
运输条件	Blue Ice
存放说明	4℃
参考文献	CC Chemokines and Receptors Chemokine Receptors Chemokines and Receptors in Allergy and Asthma Chemokines and Receptors in Angiogenesis Human CD Marker Products Regulatory T Cells (Tregs) T Cell Migration/Adhesion Th17 Cells Th2 Cells Th22 Cells

参考图片

Detection of CCR4 in Human PBMCs by Flow Cytometry. Human peripheral blood mononuclear cells (PBMCs) were stained with Mouse Anti-Human CD3 epsilon PE‑conjugated Monoclonal Antibody (Catalog # FAB100P) and either (A) Mouse Anti-Human/Rat CCR4 Alexa Fluor® 647‑conjugated Monoclonal Antibody (Catalog # FAB1567R) or (B) Mouse IgG_2B Alexa Fluor 647 Isotype Control (Catalog # IC0041R). View our protocol for Staining Membrane-associated Proteins.