| 货号 | FAB1567G-025 |
| 别名 | C-C chemokine receptor type 4; C-C CKR-4; CC-CKR-4HGCN:14099; CCR-4; CD194 antigen; CD194; chemokine (C-C motif) receptor 4; chemokine (C-C) receptor 4; ChemR13; CKR4MGC88293; CMKBR4k5-5; K5-5 |
| 反应种属 | Human/Rat |
| 应用 | Flow Cytometry(5 µL/106cells) |
| 目标/特异性 | Stains human CCR4-transfected cell lines but not the corresponding parent cell lines. Also detects human CCR4 on human PBLs and platelets and rat CCR4 on rat splenocytes. |
| 使用方法 | Flow Cytometry: 5 µL/106cells |
| 来源 | The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below. |
| 产品组分 |
| 供应商 | R&D Systems |
| Entrez Gene IDs | 1233 (Human); 12773 (Mouse); 171054 (Rat) |
| 纯化方式 | Protein A or G purified from hybridoma culture supernatant |
| 免疫原 | Human CCR4 transfectants Met1-Leu360 Accession # P51679 |
| 生物活性 | Human, Rat |
| 标记 | Alexa Fluor 488 |
| 背景 | CCR4, also known as CD194, is a G protein-linked seven transmembrane domain chemokine receptor that binds the chemokines CCL17/TARC and CCL22/MDC. Current evidence suggests that CCR4 expression is associated with CLA+, Th-17 and Th-2 type T cells, and with CD4+CD30+ thymocytes and platelets. CCR4 expression has also been reported on mature dendritic cells. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 参考文献 |
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Detection of CCR4 in Human PBMCs by Flow Cytometry. Human peripheral blood mononuclear cells (PBMCs) were stained with Mouse Anti-Human CD3 epsilon APC‑conjugated Monoclonal Antibody (Catalog # FAB100A) and either (A) Mouse Anti-Human/Rat CCR4 Alexa Fluor® 488‑conjugated Monoclonal Antibody (Catalog # FAB1567G) or (B) Mouse IgG2B Alexa Fluor 488 Isotype Control (Catalog # IC0041G). View our protocol for Staining Membrane-associated Proteins. |
