Human/Rat CCR4 Allophycocyanin MAb (Clone 205410) (25 TESTS)【科瑞奥博】

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Human/Rat CCR4 Allophycocyanin MAb (Clone 205410) (25 TESTS)

货号： FAB1567A-025 基本售价： 1824.2 元规格： 25 Tests

产品信息

概述
货号	FAB1567A-025
简介	Clone 205410 was used by HLDA to establish CD designation
别名	C-C chemokine receptor type 4; C-C CKR-4; CC-CKR-4HGCN:14099; CCR-4; CD194 antigen; CD194; chemokine (C-C motif) receptor 4; chemokine (C-C) receptor 4; ChemR13; CKR4MGC88293; CMKBR4k5-5; K5-5
反应种属	Human/Rat
应用	Flow Cytometry(10 µL/10⁶cells)
目标/特异性	Stains human CCR4-transfected cell lines but not the corresponding parent cell lines. Also detects human CCR4 on human PBLs and platelets and rat CCR4 on rat splenocytes.
使用方法	Flow Cytometry: 10 µL/10⁶cells
来源	The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
产品组分

性能
供应商	R&D Systems
Entrez Gene IDs	1233 (Human); 12773 (Mouse); 171054 (Rat)
应用文献
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions. Elevated frequencies of highly activated CD4+ T cells in HIV+ patients developing immune reconstitution inflammatory syndrome. Authors: Antonelli LR, Mahnke Y, Hodge JN, Porter BO, Barber DL, DerSimonian R, Greenwald JH, Roby G, Mican J, Sher A, Roederer M, Sereti I Blood, 2010;116(19):3818-27. Species: Human Sample Type: Whole Cells Application: Flow CCR2 identifies a stable population of human effector memory CD4+ T cells equipped for rapid recall response. Authors: Zhang HH, Song K, Rabin RL, Hill BJ, Perfetto SP, Roederer M, Douek DC, Siegel RM, Farber JM J. Immunol., 2010;185(11):6646-63. Species: Human Sample Type: Whole Cells Application: Flow Chemokine responsiveness of CD4+ CD25+ regulatory and CD4+ CD25- T cells from atopic and nonatopic donors. Authors: Ahern D, Lloyd CM, Robinson DS Allergy, 2009;64(8):1121-9. Species: Human Sample Type: Whole Cells Application: Flow
纯化方式	Protein A or G purified from hybridoma culture supernatant
免疫原	Human CCR4 transfectants Met1-Leu360 Accession # P51679
生物活性	Human, Rat
标记	APC
背景	CCR4 is a G protein-linked seven transmembrane domain chemokine receptor that binds the chemokines CCL17/TARC and CCL22/MDC. Current evidence suggests that CCR4 expression is associated with Th-2 type T cells and with platelets. CCR4 expression has also been reported in mature dendritic cells.
运输条件	Blue Ice
存放说明	4℃
参考文献	CC Chemokines and Receptors Chemokine Receptors Chemokines and Receptors in Allergy and Asthma Chemokines and Receptors in Angiogenesis Human CD Marker Products Regulatory T Cells (Tregs) T Cell Migration/Adhesion Th17 Cells Th2 Cells Th22 Cells

参考图片

Detection of CCR4 in Human Blood Lymphocytes by Flow Cytometry. Human peripheral blood lymphocytes were stained with Mouse Anti-Human CD3 epsilon PE‑conjugated Monoclonal Antibody (Catalog # FAB100P) and either (A) Mouse Anti-Human/Rat CCR4 APC‑conjugated Monoclonal Antibody (Catalog # FAB1567A) or (B) Mouse IgG_2B Allophycocyanin Isotype Control (Catalog # IC0041A). View our protocol for Staining Membrane-associated Proteins.

Detection of CCR4 in Rat Splenocytes by Flow Cytometry. Rat splenocytes were stained with Mouse Anti-Human/Rat CCR4 APC‑conjugated Monoclonal Antibody (Catalog # FAB1567A) and Anti-Rat CD3 epsilon PE-conjugated Antibody. Quadrant markers were set based on control antibody staining (Catalog # IC0041A). View our protocol for Staining Membrane-associated Proteins.