Human/Mouse CCR6 Phycoerythrin MAb (Clone 140706) (25 TESTS)【科瑞奥博】

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Human/Mouse CCR6 Phycoerythrin MAb (Clone 140706) (25 TESTS)

货号： FAB590P-025 基本售价： 1685.4 元规格： 25 Tests

产品信息

概述
货号	FAB590P-025
别名	BN-1; CC-CKR-6; CCR6; CCR-6; CD196 antigen; CD196; chemokine (C-C motif) receptor 6; CKR-L3G-protein coupled receptor 29; CKRL3LARC receptor; CMKBR6STRL22; DRY6; GPR29; GPR29C-C CKR-6; GPR-CY4; GPRCY4DRY-6; lymphocyte, 22; STRL22
反应种属	Mouse
应用	Flow Cytometry
目标/特异性	Detects mouse CCR6-transfected rat RBL cells but not the parent cell line or cells transfected with mouse CCR5. Detects human CCR6 in flow cytometry.
使用方法	Flow Cytometry: 10 µL/10⁶cells
来源	The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
产品组分

性能
供应商	R&D Systems
Entrez Gene IDs	1235 (Human); 12458 (Mouse); 308163 (Rat)
应用文献
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions. Infection of Female BWF1 Lupus Mice with Malaria Parasite Attenuates B Cell Autoreactivity by Modulating the CXCL12/CXCR4 Axis and Its Downstream Signals PI3K/AKT, NFkappaB and ERK. Authors: Badr G, Sayed A, Abdel-Maksoud M, Mohamed A, El-Amir A, Abdel-Ghaffar F, Al-Quraishy S, Mahmoud M PLoS ONE, 2015;10(4):e0125340. Species: Mouse Sample Type: Whole Cells Application: Flow Differential developmental requirement and peripheral regulation for dermal Vgamma4 and Vgamma6T17 cells in health and inflammation. Authors: Cai Y, Xue F, Fleming C, Yang J, Ding C, Ma Y, Liu M, Zhang H, Zheng J, Xiong N, Yan J Nat Commun, 2014;5(0):3986. Species: Mouse Sample Type: Whole Cells Application: Flow Cryptococcus gattii infection dampens Th1 and Th17 responses by attenuating dendritic cell function and pulmonary chemokine expression in the immunocompetent hosts. Authors: Angkasekwinai P, Sringkarin N, Supasorn O, Fungkrajai M, Wang Y, Chayakulkeeree M, Ngamskulrungroj P, Angkasekwinai N, Pattanapanyasat K Infect Immun, 2014;82(9):3880-90. Species: Mouse Sample Type: Whole Cells Application: Flow Difference in Th1 and Th17 lymphocyte adhesion to endothelium. Authors: Alcaide P, Maganto-Garcia E, Newton G, Travers R, Croce KJ, Bu DX, Luscinskas FW, Lichtman AH J. Immunol., 2012;188(3):1421-30. Species: Mouse Sample Type: Whole Cells Application: Flow Notch, Id2, and ROR gamma-t sequentially orchestrate the fetal development of lymphoid tissue inducer cells. Authors: Cherrier M, Sawa S, Eberl G J. Exp. Med., 2012;209(4):729-40. Species: Mouse Sample Type: Whole Cells Application: Flow CCR7-CCL19/CCL21-regulated dendritic cells are responsible for effectiveness of sublingual vaccination. Authors: Song JH, Kim JI, Kwon HJ, Shim DH, Parajuli N, Cuburu N, Czerkinsky C, Kweon MN J. Immunol., 2009;182(11):6851-60. Species: Mouse Sample Type: Whole Cells Application: Flow ATP drives lamina propria T(H)17 cell differentiation. Authors: Atarashi K, Nishimura J, Shima T, Umesaki Y, Yamamoto M, Onoue M, Yagita H, Ishii N, Evans R, Honda K, Takeda K Nature, 2008;455(7214):808-12. Species: Mouse Sample Type: Whole Cells Application: Flow Dendritic cells in islets of Langerhans constitutively present beta cell-derived peptides bound to their class II MHC molecules. Authors: Calderon B, Suri A, Miller MJ Proc. Natl. Acad. Sci. U.S.A., 2008;105(16):6121-6. Species: Mouse Sample Type: Whole Cells Application: Flow Both Th1 and Th17 are immunopathogenic but differ in other key biological activities. Authors: Cox CA, Shi G, Yin H, Vistica BP, Wawrousek EF, Chan CC, Gery I J. Immunol., 2008;180(11):7414-22. Species: Mouse Sample Type: Whole Cells Application: Flow Chemokine receptor CCR2 but not CCR5 or CCR6 mediates the increase in pulmonary dendritic cells during allergic airway inflammation. Authors: Robays LJ, Maes T, Lebecque S, Lira SA, Kuziel WA, Brusselle GG, Joos GF, Vermaelen KV J. Immunol., 2007;178(8):5305-11. Species: Mouse Sample Type: Whole Cells Application: Flow
纯化方式	Protein A or G purified from hybridoma culture supernatant
免疫原	RBL-1 rat basophilic leukemia cell line transfected with mouse CCR6 Met1-Met367 Accession # O54689
生物活性	Human, Mouse
标记	Phycoerythrin
背景	CCR6 is a seven transmembrane-spanning G protein-coupled receptor that binds the chemokine MIP-3 alpha and mediates the chemoattraction of B and T lymphocytes.
运输条件	Blue Ice
存放说明	4℃
参考文献	B Cell Chemotaxis, Migration, and Adhesion CC Chemokines and Receptors Chemokine Receptors Chemokines and Receptors in Allergy and Asthma Chemokines and Receptors in Angiogenesis Dendritic Cell Adhesion and Migration gamma delta T Cells Human CD Marker Products LTi Cells Monocyte Markers Natural Killer T (NKT) Cells Regulatory T Cells (Tregs) T Cell Migration/Adhesion Th17 Cells Th22 Cells

参考图片

Detection of CCR6 in Mouse Splenocytes by Flow Cytometry. Mouse splenocytes were stained with Rat Anti-Mouse B220/CD45R APC‑conjugated Monoclonal Antibody (Catalog # FAB1217A) and either (A) Rat Anti-Human/Mouse CCR6 PE‑conjugated Monoclonal Antibody (Catalog # FAB590P) or (B) Rat IgG_2A Phycoerythrin Isotype Control (Catalog # IC006P). View our protocol for Staining Membrane-associated Proteins.

Detection of CCR6 in Human Blood Lymphocytes by Flow Cytometry. Human peripheral blood lymphocytes were stained with Mouse Anti-Human CD19 APC‑conjugated Monoclonal Antibody (Catalog # FAB4867A) and either (A) Rat Anti-Human/Mouse CCR6 PE‑conjugated Monoclonal Antibody (Catalog # FAB590P) or (B) Rat IgG_2A Phycoerythrin Isotype Control (Catalog # IC006P). View our protocol for Staining Membrane-associated Proteins.