Human/Mouse CCR6 Alexa Fluor 488 MAb (Clone 140706) (25 TESTS)【科瑞奥博】

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Human/Mouse CCR6 Alexa Fluor 488 MAb (Clone 140706) (25 TESTS)

货号： FAB590G-025 基本售价： 1685.4 元规格： 25 Tests

产品信息

概述
货号	FAB590G-025
别名	BN-1; CC-CKR-6; CCR6; CCR-6; CD196 antigen; CD196; chemokine (C-C motif) receptor 6; CKR-L3G-protein coupled receptor 29; CKRL3LARC receptor; CMKBR6STRL22; DRY6; GPR29; GPR29C-C CKR-6; GPR-CY4; GPRCY4DRY-6; lymphocyte, 22; STRL22
反应种属	Mouse
应用	Flow Cytometry
目标/特异性	Detects mouse CCR6-transfected rat RBL cells but not the parent cell line or cells transfected with mouse CCR5. Detects human CCR6 in flow cytometry.
使用方法	Flow Cytometry: 5 µL/10⁶cells
来源	The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
产品组分

性能
供应商	R&D Systems
Entrez Gene IDs	1235 (Human); 12458 (Mouse); 308163 (Rat)
应用文献
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions. BILL-cadherin/cadherin-17 contributes to the survival of memory B cells. Authors: Funakoshi, Shuichi, Shimizu, Takeyuki, Numata, Osamu, Ato, Manabu, Melchers, Fritz, Ohnishi, Kazuo PLoS ONE, 2015;10(1):e0117566. Species: Mouse Sample Type: Whole Cells Application: Flow
纯化方式	Protein A or G purified from hybridoma culture supernatant
免疫原	RBL-1 rat basophilic leukemia cell line transfected with mouse CCR6 Met1-Met367 Accession # O54689
生物活性	Human, Mouse
标记	Alexa Fluor 488
背景	CCR6 is a seven transmembrane-spanning G protein-coupled receptor that binds the chemokine MIP-3 alpha and mediates the chemoattraction of B and T lymphocytes.
运输条件	Blue Ice
存放说明	4℃
参考文献	B Cell Chemotaxis, Migration, and Adhesion CC Chemokines and Receptors Chemokine Receptors Chemokines and Receptors in Allergy and Asthma Chemokines and Receptors in Angiogenesis Dendritic Cell Adhesion and Migration gamma delta T Cells Human CD Marker Products LTi Cells Monocyte Markers Natural Killer T (NKT) Cells Regulatory T Cells (Tregs) T Cell Migration/Adhesion Th17 Cells Th22 Cells

参考图片

Detection of CCR6 in Mouse Splenocytes by Flow Cytometry. Mouse splenocytes either (A) untreated or (B) treated with PMA, Calcium Ionomycin, LPS, and Recombinant Mouse IL‑23 (Catalog # 1887-ML) overnight to induce Th17 activation were stained with Rat Anti-Mouse CD4 APC‑conjugated Monoclonal Antibody (Catalog # FAB554A) and either (A) Rat Anti-Mouse CCR6 Alexa Fluor® 488‑conjugated Monoclonal Antibody (Catalog # FAB590G) or (B) Rat IgG_2A Alexa Fluor 488 Isotype Control (Catalog # IC006G). View our protocol for Staining Membrane-associated Proteins.

Detection of CCR6 in Human Blood Lymphocytes by Flow Cytometry. Human peripheral blood lymphocytes were stained with Mouse Anti-Human CD19 APC‑conjugated Monoclonal Antibody (Catalog # FAB4867A) and either (A) Rat Anti-Human/Mouse CCR6 Alexa Fluor® 488‑conjugated Monoclonal Antibody (Catalog # FAB590G) or (B) Rat IgG_2A Alexa Fluor 488 Isotype Control (Catalog # IC006G). View our protocol for Staining Membrane-associated Proteins.