Mouse CCR2 MAb (Clone 475301) (25 UG)【科瑞奥博】

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Mouse CCR2 MAb (Clone 475301) (25 UG)

货号： MAB55381-SP 基本售价： 1467.3 元规格： 25 UG

产品信息

概述
货号	MAB55381-SP
别名	C-C chemokine receptor type 2; C-C CKR-2; CC-CKR-2CKR2B; CCR2; CCR-2; CCR2A; CCR2B; CD192 antigen; CD192; chemokine (C-C motif) receptor 2; CKR2; CKR2A; CMKBR2MGC111760; FLJ78302; MCP-1 receptor; MCP-1-RMGC103828; MGC168006; Monocyte chemoattractant protein 1 receptor; monocyte chemotactic protein 1 receptor
应用	Flow Cytometry
目标/特异性	Detects mouse CCR2 transfectants but not the parental cell line in flow cytometry. Does not detect HEK293 human embryonic kidney cell line transfected with mouse CCR5 in flow cytometry.
使用方法	Flow Cytometry: 0.25 µg/10⁶cells
来源	Reconstitute at 0.5 mg/mL in sterile PBS.
产品组分

性能
供应商	R&D Systems
Entrez Gene IDs	729230 (Human); 12772 (Mouse); 60463 (Rat)
纯化方式	Protein A or G purified from hybridoma culture supernatant
免疫原	L1.2 mouse pro-B cell line transfected with mouse CCR2
生物活性	Mouse
标记	Unconjugated
溶解方法	Reconstitute at 0.5 mg/mL in sterile PBS.
背景	CCR2, also known as CD192, is a 38 kDa 7TM chemokine receptor that preferentially binds CCL2, CCL7, and CCL13. CCR2 is expressed by multiple hematopoietic cells, endothelial cells, fibroblasts, neurons, and smooth muscle cells. It functions as an HIV fusion co-factor and facilitates T cell recruitment during inflammation. Two alternate splice forms (CCR2A and CCR2B) differ only by the addition of 14 amino acids to the intracellular carboxyl terminal. Mouse CCR2 shares 67% and 95% aa sequence identity with human and rat CCR2, respectively.
运输条件	Blue Ice
存放说明	4℃
参考文献	CC Chemokines and Receptors Chemokine Receptors Chemokines and Receptors in Allergy and Asthma Chemokines and Receptors in Angiogenesis Cytokine and Growth Factor Receptors on VSMC Macrophage Activation Markers Monocyte Markers Myeloid Lineage Markers Myeloid-derived Suppressor Cells (MDSC) Neuroinflammation Receptors in the Jak/STAT Pathway Regulatory T Cells (Tregs) T Cell Migration/Adhesion

参考图片

Detection of CCR2 in NS0 Mouse Cell Line Transfected with Mouse CCR2 and eGFP by Flow Cytometry. NS0 mouse myeloma cell line transfected with either (A) mouse CCR2 or (B) irrelevant transfectants and eGFP was stained with Rat Anti-Mouse/Rat CCR2 Monoclonal Antibody (Catalog # MAB55381) followed by Phycoerythrin-conjugated Anti-Rat IgG Secondary Antibody (Catalog # F0105B). Quadrant markers were set based on isotype control (Rat IgG_2B,Catalog #MAB0061; data not shown). View our protocol for Staining Membrane-associated Proteins.