Mouse CD161/NK1.1 Allophycocyanin MAb (Clone PK136) (25 TESTS)
货号：
FAB8319A-025 基本售价：
1407.8 元 规格：
25 Tests
产品信息
概述| 货号 | FAB8319A-025 |
| 别名 | CD161 antigen; CD161; CD161c; CLEC5BC-type lectin domain family 5 member B; HNKR-P1a; killer cell lectin-like receptor subfamily B member 1; killer cell lectin-like receptor subfamily B, member 1; Klrb1c; Ly55c; Ly-59; Natural killer cell surface protein P1A; NKR-P1; NKR-P1AMGC138614; NKRP1ANKR |
| 反应种属 | Mouse |
| 应用 | Flow Cytometry(10 µL/106cells)
|
| 目标/特异性 | Detects mouse CD161/NK1.1 by flow cytometry |
| 使用方法 | Flow Cytometry: 10 µL/106cells
|
| 来源 | The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below. |
| 产品组分 | |
性能| 供应商 | R&D Systems |
| Entrez Gene IDs | 17059 (Mouse) |
| 纯化方式 | Protein A or G purified from hybridoma culture supernatant |
| 免疫原 | Mouse NK-1+ splenocytes and bone marrow cells |
| 生物活性 | Mouse |
| 标记 | Allophycocyanin |
| 背景 | CD161, also known as NK1.1, KLRB-1C, Ly-55, and NKR-P1c, is a 28 kDa type 2 transmembrane protein in the Killer Cell Lectin-like Receptor family. CD161 is expressed as a disulfide-linked homodimer on the surface of NK cells and subpopulations of NKT, CD4+, CD8+, and gamma /δ T cells. Its cross-linking on NK cells induces cytolytic activity, and on CD4 cells it promotes IgE production and the expansion of Th2 responses. Mature mouse CD161 consists of a 45 amino acid (aa) cytoplasmic domain, a 21 aa transmembrane segment, and a 157 aa extracellular domain with one C-type lectin domain. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 参考文献 | - C-type Lectin Family
- gamma delta T Cells
- Group 1 ILCs
- Group 2 ILCs
- Isolation, Culture, and Identification of Natural Killer Cells
- LTi Cells
- Natural Killer T (NKT) Cells
- NCR+ILC3
- Th17 Cells
|
参考图片Detection of CD161/NK1.1 in C57BL/6 Mouse Splenocytes by Flow Cytometry. C57BL/6 mouse splenocytes were stained with Rat Anti-Mouse NKp46/NCR1 PE‑conjugated Monoclonal Antibody (Catalog # FAB22252P) and either (A) Mouse Anti-Mouse CD161/NK1.1 APC‑conjugated Monoclonal Antibody (Catalog # FAB8319A) or (B) Mouse IgG 2A Allophycocyanin Isotype Control (Catalog # IC003A). View our protocol for Staining Membrane-associated Proteins. |
