Mouse CXCR4 Phycoerythrin MAb (Clone 247506) (25 TESTS)【科瑞奥博】

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Mouse CXCR4 Phycoerythrin MAb (Clone 247506) (25 TESTS)

货号： FAB21651P-025 基本售价： 1407.8 元规格： 25 Tests

产品信息

概述
货号	FAB21651P-025
别名	CD184; chemokine (C-X-C motif) receptor 4; chemokine (C-X-C motif), receptor 4 (fusin); C-X-C chemokine receptor type 4; CXC-R4; CXCR-4; D2S201ESDF-1 receptor; FB22; Fusin; HM89NPYRL; HSY3RR; LAP3; LCR1; LESTRCD184 antigen; Leukocyte-derived seven transmembrane domain receptor; leukocyte-derived seven-transmembrane-domain receptor; lipopolysaccharide-associated protein 3; neuropeptide Y receptor Y3; NPY3RWHIM; NPYR; NPYY3R; seven transmembrane helix receptor; seven-transmembrane-segment receptor, spleen; Stromal cell-derived factor 1 receptor
反应种属	Mouse
应用	Flow Cytometry(10 µL/10⁶cells)
目标/特异性	Detects mouse CXCR4 transfectants. Does not stain irrelevant transfectants.
使用方法	Flow Cytometry: 10 µL/10⁶cells
来源	The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
产品组分

性能
供应商	R&D Systems
Entrez Gene IDs	7852 (Human); 12767 (Mouse); 60628 (Rat); 483900 (Canine); 493676 (Feline)
应用文献
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions. Infection of Female BWF1 Lupus Mice with Malaria Parasite Attenuates B Cell Autoreactivity by Modulating the CXCL12/CXCR4 Axis and Its Downstream Signals PI3K/AKT, NFkappaB and ERK. Authors: Badr G, Sayed A, Abdel-Maksoud M, Mohamed A, El-Amir A, Abdel-Ghaffar F, Al-Quraishy S, Mahmoud M PLoS ONE, 2015;10(4):e0125340. Species: Mouse Sample Type: Whole Cells Application: Flow Chemokine receptor CX3CR1 contributes to macrophage survival in tumor metastasis. Authors: Zheng, Jiao, Yang, Min, Shao, Jianghua, Miao, Yanju, Han, Jiahuai, Du, Jie Mol Cancer, 2013;12(1):141. Species: Mouse Sample Type: Whole Cells Application: Flow G protein-coupled receptor kinase-3-deficient mice exhibit WHIM syndrome features and attenuated inflammatory responses. Authors: Tarrant, Teresa K, Billard, Matthew, Timoshchenko, Roman G, McGinnis, Marcus W, Serafin, D Stephe, Foreman, Oded, Esserman, Denise A, Chao, Nelson J, Lento, William, Lee, David M, Patel, Dhavalku, Siderovski, David P J Leukoc Biol, 2013;94(6):1243-51. Species: Mouse Sample Type: whole cells Application: Flow MicroRNA126 contributes to granulocyte colony-stimulating factor-induced hematopoietic progenitor cell mobilization by reducing the expression of vascular cell adhesion molecule 1. Authors: Salvucci O, Jiang K, Gasperini P Haematologica, 2012;97(6):818-26. Species: Mouse Sample Type: Whole Cells Application: Flow CXCL12 enhances exogenous CD4+CD25+ T cell migration and prevents embryo loss in non-obese diabetic mice. Authors: Lin Y, Xu L, Jin H, Zhong Y, Di J, Lin QD Fertil. Steril., 2009;91(6):2687-96. Species: Mouse Sample Type: Whole Cells Application: Flow The angiogenic response is dictated by beta3 integrin on bone marrow-derived cells. Authors: Feng W, McCabe NP, Mahabeleshwar GH, Somanath PR, Phillips DR, Byzova TV J. Cell Biol., 2008;183(6):1145-57. Species: Mouse Sample Type: Whole Cells Application: Flow
纯化方式	Protein A or G purified from hybridoma culture supernatant
免疫原	Y3 rat myeloid cell line transfected with mouse CXCR4 Met1-Ser359 Accession # P70658
生物活性	Mouse
标记	Phycoerythrin
背景	CXCR4 is a G-protein-linked seven transmembrane spanning receptor that binds stromal cell-derived factor-1 (SDF-1). CXCR4 acts as a co-factor for T-cell tropic HIV-1 and-2 viral entry into cells.
运输条件	Blue Ice
存放说明	4℃
参考文献	Acute Myeloid Leukemia B Cell Chemotaxis, Migration, and Adhesion B Cell Markers Cancer Biomarkers Cancer Stem Cell Markers Chemokine Receptors Chemokines and Receptors in Allergy and Asthma Chemokines and Receptors in Angiogenesis Chemokines and Receptors in Tfh Cell Differentiation and Function CXCR4: A Receptor for Extracellular Ubiquitin Cytokine Upregulation of HIV Coreceptors Endothelial Cell Differentiation Markers Endothelial Progenitor and Endothelial Cell Markers Endothelial Progenitor Cell Markers gamma delta T Cells Hematopoietic Stem Cell Markers Hepatic Endoderm Hepatic Endoderm Cell Markers HIF Transcription Factors Human CD Marker Products Infectious Diseases Megakaryocytes Neural Stem Cell Markers Neuroinflammation Receptors in the Jak/STAT Pathway Regulatory T Cells (Tregs) Somite Markers T Cell Migration/Adhesion Th2 Cells

参考图片

Detection of CXCR4 in Mouse Thymocytes by Flow Cytometry. Mouse thymocytes were stained with Rat Anti-Mouse CXCR4 PE‑conjugated Monoclonal Antibody (Catalog # FAB21651P, filled histogram) or isotype control antibody (Catalog # IC013P, open histogram). View our protocol for Staining Membrane-associated Proteins.