Mouse CD11b/Integrin alpha M Fluorescein MAb (Clone M1/70) (25 TESTS)【科瑞奥博】

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Mouse CD11b/Integrin alpha M Fluorescein MAb (Clone M1/70) (25 TESTS)

货号： FAB1124F-025 基本售价： 1259.1 元规格： 25 Tests

产品信息

概述
货号	FAB1124F-025
别名	antigen CD11b (p170); CD11 antigen-like family member B; CD11b antigen; CD11b; CD11Bintegrin, alpha M (complement component receptor 3, alpha; also known as CD11b(p170), macrophage antigen alpha polypeptide); Cell surface glycoprotein MAC-1 subunit alpha; CR-3 alpha chain; CR3AMGC117044; Integrin alpha M; integrin alpha-M; integrin, alpha M (complement component 3 receptor 3 subunit); ITGAM; Leukocyte adhesion receptor MO1; MAC-1; MAC1A; macrophage antigen alpha polypeptide; MO1A; neutrophil adherence receptor alpha-M subunit; Neutrophil adherence receptor; SLEB6
反应种属	Mouse
应用	Flow Cytometry(10 µL/10⁶cells)
目标/特异性	Detects mouse Integrin alpha M/CD11b. Cross-reaction with human Integrin alpha M has been reported (1, 2).
使用方法	Flow Cytometry: 10 µL/10⁶cells
来源	The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
产品组分

性能
供应商	R&D Systems
Entrez Gene IDs	3684 (Human); 16409 (Mouse)
应用文献
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions. Regulation of Leishmania (L.) amazonensis protein expression by host T cell dependent responses: differential expression of oligopeptidase B, tryparedoxin peroxidase and HSP70 isoforms in amastigotes isolated from BALB/c and BALB/c nude mice. Authors: Teixeira P, Velasquez L, Lepique A, de Rezende E, Bonatto J, Barcinski M, Cunha-Neto E, Stolf B PLoS Negl Trop Dis, 2015;9(2):e0003411. Species: Mouse Sample Type: cells Application: Flow
纯化方式	Protein A or G purified from hybridoma culture supernatant
免疫原	Con A-activated C57BL/10 splenocytes
生物活性	Mouse
标记	Fluorescein
背景	The Integrin family proteins are heterodimeric transmembrane receptors composed of an alpha and a beta subunit. The Integrin alpha M subunit, also known as MAC-1 alpha subunit or CD11b, combines with the Integrin beta 2 subunit (CD18) to form the non-covalent heterodimer Integrin alpha M/ beta 2, also known as MAC-1 and Complement Receptor type 3 (CR3). Integrin alpha M/ beta 2 is expressed on granulocytes, macrophages, dendritic cells and natural killer cells. Upon activation, alpha M/ beta 2 can bind several ligands (including ICAM-1, Fibrinogen, and the C3 Complement Fragment, C3bi) to mediate phagocyte adhesion, migration and ingestion of complement-opsonized particles.
运输条件	Blue Ice
存放说明	4℃
参考文献	Acute Lymphoblastic Leukemia Acute Myeloid Leukemia Adhesion Molecules Adhesive Interactions in Allergy and Asthma B Cell Chemotaxis, Migration, and Adhesion B Cell Markers Basophils Common Macrophage Markers Conventional/Classical Dendritic Cells Granulocyte Markers HGF/SF Activation of Integrins Human CD Marker Products ICC / IHC Images: CD11b/Integrin alpha M Inflammatory/Monocyte-derived Dendritic Cells Integrin Ligands at a Glance (J. Cell. Sci.) Integrin Subunit Interactions Integrins and Associated Molecules Isolation, Culture, and Identification of Natural Killer Cells Langerhans and Dermal Dendritic Cells Monocyte Markers Mouse Tissue-Resident Macrophage Markers Myeloid Lineage Markers Myeloid-derived Suppressor Cells (MDSC) Neuroinflammation Neutrophils Plasmacytoid Dendritic Cells T Cell Migration/Adhesion

参考图片

Detection of Integrin alpha M/CD11b in Mouse Peripheral Blood Cells by Flow Cytometry. Mouse peripheral blood cells were stained with Rat Anti-Mouse Integrin alpha M/CD11b Fluorescein‑conjugated Monoclonal Antibody (Catalog # FAB1124F, filled histogram) or isotype control antibody (Catalog # IC013F, open histogram). View our protocol for Staining Membrane-associated Proteins.