Mouse CD4 Phycoerythrin MAb (Clone GK1.5) (25 TESTS)【科瑞奥博】

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Mouse CD4 Phycoerythrin MAb (Clone GK1.5) (25 TESTS)

货号： FAB554P-025 基本售价： 832.8 元规格： 25 Tests

产品信息

概述
货号	FAB554P-025
别名	CD4 antigen (p55); CD4 antigen; CD4 molecule; CD4 receptor; CD4; CD4mut; T-cell surface antigen T4/Leu-3; T-cell surface glycoprotein CD4
反应种属	Mouse
应用	Flow Cytometry(10 µL/10⁶cells)
目标/特异性	Reacts with mouse CD4, an antigen co-receptor on the T cell surface which interacts with MHC II molecules on antigen presenting cells.
使用方法	Flow Cytometry: 10 µL/10⁶cells
来源	The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
产品组分

性能
供应商	R&D Systems
Entrez Gene IDs	920 (Human); 12504 (Mouse); 24932 (Rat); 403931 (Canine); 493775 (Feline)
应用文献
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions. Steady state migratory RelB+ langerin+ dermal dendritic cells mediate peripheral induction of antigen-specific CD4+ CD25+ Foxp3+ regulatory T cells. Authors: Azukizawa H, Dohler A, Kanazawa N, Nayak A, Lipp M, Malissen B, Autenrieth I, Katayama I, Riemann M, Weih F, Berberich-Siebelt F, Lutz MB Eur. J. Immunol., 2011;41(5):1420-34. Species: Mouse Sample Type: Whole Cells Application: Flow Natural IgM is required for suppression of inflammatory arthritis by apoptotic cells. Authors: Notley CA, Brown MA, Wright GP, Ehrenstein MR J. Immunol., 2011;186(8):4967-72. Species: Mouse Sample Type: Whole Cells Application: Flow Differential IL-23 requirement for IL-22 and IL-17A production during innate immunity against Salmonella enterica serovar Enteritidis. Authors: Siegemund S, Schutze N, Schulz S, Wolk K, Nasilowska K, Straubinger RK, Sabat R, Alber G Int. Immunol., 2009;21(5):555-65. Species: Mouse Sample Type: Whole Cells Application: Flow
纯化方式	Protein A or G purified from hybridoma culture supernatant
免疫原	Mouse CTL clone V4
生物活性	Mouse
标记	Phycoerythrin
背景	CD4 is a type I membrane glycoprotein belonging to the immunoglobulin superfamily. It is expressed predominantly on thymocytes and a subset of mature T lymphocytes. CD4 functions in collaboration with the T cell receptor in the recognition of peptide antigens that are presented by class II major histocompatibility complexes. CD4 also has been shown to be a coreceptor of HIV entry and specifically binds gp120, the external envelope glycoprotein of HIV.
运输条件	Blue Ice
存放说明	4℃
参考文献	Conventional/Classical Dendritic Cells gamma delta T Cells Human CD Marker Products ICC / IHC Images: CD4 Infectious Diseases Leukocyte Receptors/Markers in Allergy and Asthma Leukocyte Receptors/Markers in Tfh Cell Differentiation and Function LTi Cells Lymphoid Lineage Markers Natural Killer T (NKT) Cells Regulatory T Cells (Tregs) Th1 Cells Th17 Cells Th2 Cells Th22 Cells Th9 Cells

参考图片

Detection of CD4 in Mouse Splenocytes by Flow Cytometry. Mouse splenocytes were stained with Rat Anti-Mouse CD3 APC‑conjugated Monoclonal Antibody (Catalog # FAB4841A) and either (A) Rat Anti-Mouse CD4 PE‑conjugated Monoclonal Antibody (Catalog # FAB554P) or (B) Rat IgG_2B Phycoerythrin Isotype Control (Catalog # IC013P). View our protocol for Staining Membrane-associated Proteins.