CD252 pure, functional grade, mouse
货号:
130-098-856 基本售价:
询价 规格:
EA
产品信息
概述货号 | 130-098-856 |
描述 | Clone RM134L recognizes CD252 (OX40L), a ligand of OX40 receptor, belonging to the TNF superfamily. Expression of CD252 can be induced on B cells, dendritic cells, macrophages, mast cells, NK cells, endothelial cells and smooth muscle cells. Expression of the cognate receptor OX40, is found on activated CD4 cells, CD8 cells, regulatory T cells, NKT cells, NK cells and neutrophils, but the function of OX40 signalling is extensively studied only in T cells. CD252 (OX40L)-OX40 interaction promotes the proliferation and surival of effector T cells, modulates cytokine production, suppresses the activity of natural regulatory T cells (nTreg) and inhibits the generation of inducible Treg cells. |
别名 | TNFSF4, Ath-1, Ath1, CD134L, OX40L, Txgp1, Txgp1l, gp34 |
克隆号 | RM134L |
同种亚型 | rat IgG2bκ |