CD152 pure, functional grade, mouse
货号：
130-097-503 基本售价：
询价 规格：
EA
产品信息
概述| 货号 | 130-097-503 |
| 描述 | The monoclonal antibody UC10-4B9 reacts with CD152, also known as CTLA-4 (cytotoxic T lymphocyte antigen-4), which is a 33 kDa member of the immunoglobin superfamily and is expressed on activated T cells at a low level. CTLA-4 and CD28 have similarities concerning B7 family counter-receptors. While CD28 delivers a costimulary signal in T cell activation, CD152 restricts the progression of T cells to an activated state by inhibiting IL-2 secretion and cellular proliferation. A large proportion of CTLA-4 is intracellular localized. For a complete detection it may be necessary to assess intracellular staining in addition to surface expression of CD152. |
| 别名 | CTLA4, CTLA-4, Ly-56 |
| 克隆号 | UC10-4B9 |
| 同种亚型 | hamster IgG1 |
