Anti-b-Catenin-FITC, human, mouse
货号：
130-107-119 基本售价：
询价 规格：
EA
产品信息
概述| 货号 | 130-107-119 |
| 描述 | Clone REA480 recognizes the human and mouse β-catenin antigen, a 92 kDa dual function protein regulating the coordination of cell-cell adhesion and gene transcription. β-catenin is a subunit of the cadherin protein complex and acts as an intracellular signal transducer in the Wnt signaling pathway. As a component of adherens junctions, β-catenin binds cadherins, Tcf family transcription factors, and the tumor suppressor adenomatous polyposis coli (APC). Mutations and overexpression of β-catenin are associated with many cancers, including hepatocellular carcinoma, colorectal carcinoma, lung cancer, malignant breast tumors as well as ovarian and endometrial cancer. Additional information: Clone REA480 displays negligible binding to Fc receptors. |
| 别名 | CTNNB1, CTNNB, MRD19, armadillo, CTNB1, Beta-catenin, Catnb |
| 克隆号 | REA480 |
| 同种亚型 | recombinant human IgG1 |
