CD40 pure, mouse - Funct Grade
货号：
130-093-022 基本售价：
询价 规格：
EA
产品信息
概述| 货号 | 130-093-022 |
| 描述 | Clone FGK45.5 recognizes the mouse CD40 antigen, a 40–50 kDa glycoprotein and member of the tumor necrosis factor receptor (TNFR) superfamily. CD40 is expressed on B lymphocytes, macrophages, and dendritic cells and is an important costimulatory molecule for B cells as well as dendritic cells, monocytes, and other antigen-presenting cells (APCs). The interaction of CD40 on B cells with its ligand CD154 is involved in B cell activation and differentiation; engagement of CD40 on dendritic cells leads to maturation. Clone FGK45 can be used for blocking of CD40/CD154 interaction and for in vitroandin vivo activation of CD40-expressing APCs. |
| 别名 | Bp50, gp39, HIGM1, IGM, IMD3, T-BAM, TRAP, TNFRSF5, p50 |
| 克隆号 | FGK45.5 |
| 同种亚型 | rat IgG2a |
