CD278 (ICOS)-PE, h&m&r 30 tests
货号：
130-100-729 基本售价：
询价 规格：
30 tests
产品信息
概述| 货号 | 130-100-729 |
| 描述 | Clone REA192 recognizes CD278 (ICOS), which belongs to the CD28 family of proteins. CD28 family members are co-stimulatory receptor molecules, contain single immunoglobulin V-like domain, and belong to the immunoglobulin superfamily. CD287 recognizes ICOSL (inducible T cell co-stimulator ligand) as ligand and its expression is induced on activated T cells. Enhanced expression of CD278 is also observed on T cells, followed by co-stimulation of T cells via CD28. Further expression of CD278 is found on B cells, monocytes, and dendritic cells. Crosslinking of ICOS on T cell surface in the presence of primary stimulation signal leads to T cell proliferation and differentiation. In addition, CD278 plays role in Tʜ cell differentiation, effector T cell function, and isotype class switching.Additional information: Clone REA192 displays negligible binding to Fc receptors. |
| 别名 | ICOS, AILIM, CVID1 |
| 克隆号 | REA192 |
| 同种亚型 | recombinant human IgG1 |
